ArticleGland surgery2026
A randomized controlled trial: application of inactivated
Article in Gland surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07460297 (Pseudomonas Aeruginosa Injection Combined With Polyvinylpyrrolidone-Iodine in Immediate Breast Reconstruction Surgery With Implants:a Randomized Controlled Trial), which is not on this map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Pseudomonas Aeruginosa Injection Combined With Polyvinylpyrrolidone-Iodine in Immediate Breast Reconstruction Surgery With Implants:a Randomized Controlled Trial
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0 citing papers in PubMed.
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4 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Background: Breast cancer is one of the most commonly diagnosed malignancies worldwide. For patients undergoing nipple-sparing mastectomy with immediate prosthetic reconstruction (NSM-IPR), optimizing postoperative recovery and reducing complications are critical. Prolonged postoperative drainage is a common issue that increases infection risk and prolongs hospital stay. This study aimed to evaluate the effect of an inactivated Methods: This was a single-center, prospective, four-arm parallel-group randomized controlled trial. A total of 100 patients were randomly assigned in a 1:1:1:1 ratio to receive either low-, medium-, or high-concentration inactivated PAP immersion, or povidone-iodine alone (control). Outcome assessors were blinded. Therapeutic efficacy was assessed, including total drainage volume, drainage duration, complications, and cosmetic outcomes at 3 months postoperatively. Results: Total drainage volume was significantly lower in all PAP groups compared with the control group (low-concentration: 578.4±39.34 mL, medium-concentration: 477.8±35.53 mL, high-concentration: 444.8±34.26 mL Conclusions: The combination of inactivated PAP and povidone-iodine reduces postoperative drainage volume, shortens drainage time, and may improve cosmetic outcomes in patients undergoing NSM-IPR. Trial Registration: ClinicalTrials.gov NCT07460297.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.