Evidence map›Paper›PMID 42591721›Full record

ReviewFrontiers in pharmacology2026

Ferulic acid: a liver protector.

Yuqiu Zhang, Xinghe Wang, Xinyue Sun, Jianan Dai

Abstract readReview
In one paragraph

Review in Frontiers in pharmacology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yuqiu ZhangSuining County Traditional Chinese Medicine Hospital, Xuzhou, Jiangsu, China.
Xinghe WangCollege of Animal Science and Veterinary Medicine, Shenyang Agricultural University, Shenyang, Liaoning, China.
Xinyue SunHeilongjiang University of Chinese Medicine, Harbin, Heilongjiang, China.
Jianan DaiSuining County Traditional Chinese Medicine Hospital, Xuzhou, Jiangsu, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ferulic acid (FA) is a phenolic acid found in plants, such as wheat, corn, beet, etc. It is an important active ingredient in many herbal medicines. FA has been reported to have a variety of biological activities, especially in the resistance to oxidative stress, inflammation, vascular endothelial damage, fibrosis, apoptosis, and platelet aggregation. Because FA has advantages of high activities, low cost, non-toxic, good safety and stable structure. So it is widely used in food additives, medicine, healthcare products, and cosmetics. Numerous studies have shown the protective effects of FA and its derivatives on the liver. This paper reviews the recent research progress of FA and its derivatives in preventing and curing liver damages induced by various different factors, including the effects of FA and its derivatives on physicochemical factors induced liver injury, liver tumors, alcoholic liver disease, non-alcoholic fatty liver disease, liver metabolic disorder of diabetics, and hepatotoxicity of aflatoxin B1. The aim of this review is to provide reference for the research and application of FA and its derivatives in the prevention and treatment of liver diseases.

Indexed as

antioxidantferulic acidliver damagepreventiontreatment

Identifiers

PMID42591721
PMCPMC13462595

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.