Evidence map›Paper›PMID 42591720›Full record

ArticleTranslational pediatrics2026

From autism to obesity and beyond: mapping global trends and gaps in pediatric gut microbiota interventions-a bibliometric analysis.

Congcong Ma, Jian Zhao, Chen Wang, Bo Meng, Guixiang Yao, Hengbo Ye

Abstract read
In one paragraph

Article in Translational pediatrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Congcong MaDepartment of Pediatrics, Taian Maternity and Child Health Hospital, Taian, China.
Jian ZhaoDepartment of Pediatrics, Taian Maternity and Child Health Hospital, Taian, China.
Chen WangEmergency and Intensive Medicine Department, The First People's Hospital of Taian, Taian, China.
Bo MengEmergency and Intensive Medicine Department, The First People's Hospital of Taian, Taian, China.
Guixiang YaoState Key Laboratory for Innovation and Transformation of Luobing Theory, Jinan, China.ORCID https://orcid.org/0009-0006-5843-5762
Hengbo YeDepartment of Pediatrics, Taian Maternity and Child Health Hospital, Taian, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Pediatric gut microbiota interventions are increasingly applied in conditions such as autism spectrum disorder (ASD), obesity, and malnutrition; however, the global research structure and thematic trends remain unclear. This study aimed to map the global research landscape of pediatric gut microbiota interventions from 2010 to 2025, characterizing publication trends, geographic and institutional distribution, collaboration networks, and thematic evolution, in order to identify research hotspots and evidence gaps that should guide future priorities. Methods: Publications from January 1, 2010, to June 30, 2025, were retrieved from the Web of Science Core Collection (WoSCC) using predefined search terms. Microsoft Excel 2021, VOSviewer 1.6.19, CiteSpace 6.2.4, and the R package bibliometrix 4.0.0 were employed to analyze publication trends, geographic distribution, institutional and author collaborations, highly cited works, and keyword co-occurrence. Results: A total of 1,915 articles involving 12,308 authors across 546 journals were identified, citing 39,956 references and generating 3,510 unique keywords. Global output has increased markedly over 15 years, with China and the United States forming a "dual-core" dominance. Only 27.12% of the studies resulted from multi-country (international) collaborations, indicating limited cross-regional partnerships. Research hotspots have centered on ASD, obesity, and nutritional disorders, while developmental and behavioral outcomes have been underrepresented. Personalized nutrition, microbiota-brain-behavior links, and multi-omics integration have emerged as growing themes. Conclusions: This bibliometric study maps the global landscape of pediatric gut microbiota interventions, revealing rapid expansion but thematic imbalance. Greater multinational collaboration and broader inclusion of developmental health endpoints emerge as key priorities for the future research agenda.

Indexed as

bibliometric analysisglobal trendsinterventionPediatric gut microbiotaresearch gaps

Identifiers

PMID42591720
PMCPMC13462947

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.