ArticleGland surgery2026
Low prealbumin predicts early recurrence after pancreatic cancer surgery: a retrospective cohort study.
Article in Gland surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Early recurrence after curative resection for pancreatic ductal adenocarcinoma (PDAC) is linked to poor survival, but the prognostic role of host nutritional status is uncertain. We sought to identify independent predictors of early recurrence after surgery. Methods: Fifty-seven patients who underwent pancreaticoduodenectomy or radical antegrade modular pancreaticosplenectomy for PDAC between March 2021 and December 2023 were retrospectively reviewed. Early recurrence was defined as recurrence within 1 year after surgery, whereas the non-early recurrence group included patients with recurrence after 1 year and those without recurrence during follow-up. Clinicopathologic and nutritional variables were analyzed using univariable and multivariable Cox proportional hazards models. Clinical differences between early-recurrence and non-early-recurrence groups were also assessed. Results: In the univariable analysis, N2 stage [hazard ratio (HR) 3.43, P=0.03], resection margin <1 mm (HR 2.78, P=0.02), and prealbumin <20 mg/dL (HR 3.31, P=0.02) were significantly associated with early recurrence. In multivariable analysis, low prealbumin remained independently associated with early recurrence (HR 4.82, P=0.005). Group comparison further demonstrated higher frequencies of margin <1 mm (55.0% Conclusions: Low preoperative prealbumin level remained consistently associated with early recurrence after curative PDAC resection. Margin status and nodal burden were associated with recurrence but lacked independent significance. Incorporating nutritional assessment into perioperative management may improve risk stratification and guide personalized postoperative surveillance.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.