ArticleOrthopaedic journal of sports medicine2026
Association of Donor Characteristics and Graft Storage Time with Survivorship of Osteochondral Allograft Transplantation in the Knee.
Article in Orthopaedic journal of sports medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: The effect of donor tissue characteristics on osteochondral allograft (OCA) efficacy for treating chondral and osteochondral lesions of the knee is poorly understood. Studies on graft storage time show inconsistent effects on clinical outcomes, and research on donor-specific factors remains limited. Purpose: To (1) assess the association between donor characteristics and graft storage time with allograft recipient survivorship; and (2) determine whether patient-reported outcomes and satisfaction differed across donor characteristics. Study Design: Cohort study; Level of evidence, 3. Methods: A total of 220 patients (236 knees) who underwent primary fresh OCA transplantation of the knee with a minimum 2-year follow-up were included in this study. Patients with degenerative indications were excluded. Failure (defined as further procedure such as removal or revision) and survivorship rates were compared between patients receiving OCA grafts from donors aged ≤20 or >20 years, with a body mass index (BMI) ≤30 or >30 kg/m Results: The mean follow-up was 8.2 years. Grafts from older donors (>20 years) had a significantly higher failure rate than grafts from younger donors (11.7% vs 3.7%; Conclusion: These findings suggest that donor age should be considered for OCA transplantation and that shorter graft storage times, donor BMI, and sex matching may not be required for successful clinical outcomes.
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