Evidence map›Paper›PMID 42591354›Full record

ArticleFrontiers in public health2026

Natural language processing-driven knowledge graphs for transformative public health intelligence and research datasets in urgent and emergency care.

Chris Humphries, Atul Anand, Arlene Casey, Wendy Chapman, Kathy Harrison, James M Hillis, Edward James, Donald J MacIntyre, Kenneth Nicholson, Lisa Schölin and 3 more

Abstract read
In one paragraph

Article in Frontiers in public health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Chris HumphriesGenerative AI Laboratory, School of Informatics, University of Edinburgh, Edinburgh, United Kingdom.
Atul AnandCentre for Cardiovascular Science, University of Edinburgh, Edinburgh, United Kingdom.
Arlene CaseyCentre for Population Health Sciences, University of Edinburgh, Edinburgh, United Kingdom.
Wendy ChapmanClinical Informatics Center, University of Texas Southwestern Medical Center, Dallas, TX, United States.
Kathy HarrisonCentre for Population Health Sciences, University of Edinburgh, Edinburgh, United Kingdom.
James M HillisHarvard Medical School, Boston, MA, United States.
Edward JamesDepartment of Emergency Medicine, NHS Lothian, Edinburgh, United Kingdom.
Donald J MacIntyreGenerative AI Laboratory, School of Informatics, University of Edinburgh, Edinburgh, United Kingdom.
Kenneth NicholsonPublic Health Scotland, Edinburgh, United Kingdom.
Lisa SchölinCentre for Cardiovascular Science, University of Edinburgh, Edinburgh, United Kingdom.
R Andrew TaylorDepartment of Emergency Medicine, University of Virginia, Charlottesville, VA, United States.
Christopher TomlinsonDepartment of Biostatistics & Health Informatics, King's College London, London, United Kingdom.
David RobertsonSchool of Informatics, University of Edinburgh, Edinburgh, United Kingdom.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Urgent and emergency care generates large volumes of clinical data, yet much of the information most useful for research, surveillance, and service planning is recorded only in free-text clinical notes and never reaches the structured datasets used for analysis. As a result, the reasons patients present, the upstream pressures driving demand, and the care that was needed but unavailable remain largely invisible, with consequences that fall most heavily on people who move repeatedly across services. Existing initiatives connect previously separate records or predict future events, but neither recovers the clinical reasoning that explains why people reach crisis. In this Perspective we propose a three-layer knowledge graph architecture for urgent and emergency care: a first layer linking individual contacts into connected patient trajectories across services and time; a second recovering clinical detail lost to reductive coding; and a third capturing the reasoning behind each presentation, including barriers to care and intended but unavailable services. We describe why recent advances in natural language processing and artificial intelligence make this architecture achievable, assess the current evidence - strong for each component, though the integrated architecture awaits validation - and set out the validation, governance, and infrastructure that implementation would require. The architecture offers a route from data volume to usable knowledge, and a means of making patterns of unmet need legible to those who plan and govern care. The constituent technologies now exist; whether this information remains invisible is increasingly a question of design rather than capability.

Indexed as

Artificial IntelligenceEmergency Medical ServicesNatural Language ProcessingPublic HealthElectronic Health RecordsHumansdata interoperabilityelectronic health recordsemergency careknowledge graphnatural language processing

Identifiers

PMID42591354
PMCPMC13461888

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.