ArticleFrontiers in digital health2026
The appropriateness of initial intravenous empirical antibiotic consumption guided by digital antimicrobial stewardship tool: a correlation with the usage of antibiotics from the access and watch groups in ten Indonesian hospitals.
Article in Frontiers in digital health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: RASPRO Indonesia Study Group for Antimicrobial Stewardship & Resistance has developed a digital antimicrobial stewardship (ASP) tool known as the e-RASPRO, which may provide a guideline for clinical decision on antibiotic prescribing for bacterial infection cases by integrating the WHO AWaRe (Access, Watch, Reserve) classification. Methods: A multicenter retrospective correlational study was conducted using aggregated monthly hospital antibiotic prescribing data. A correlation test was conducted between the mean percentage on the appropriateness of initial intravenous empirical antibiotic consumption and the mean Defined Daily Dose (DDD) of antibiotics within a year (January to December 2024) in 10 Indonesian hospitals after the socialization of e-RASPRO tool between 2022 and 2024 in four major infections. Results: There was a significant positive correlation between the mean of percentages on appropriateness of initial intravenous empirical antibiotic consumption in type I risk stratification guided by e-RASPRO tool and the mean DDD/100 patient-days of intravenous Penicillin as Access group antibiotic ( Conclusion: Appropriateness of initial intravenous empirical antibiotic consumption in type I and II risk stratification guided by e-RASPRO tool was correlated with increased consumption of Penicillin as an Access group antibiotic and decreased consumption of third-generation Cephalosporins as a Watch group antibiotic. This study did not describe a causal relationship between the use of the e-RASPRO tool and antibiotic consumption in the hospital.
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