ArticleFrontiers in neurology
White matter lesions in migraine: a single-center retrospective study of prevalence and risk factors.
Article in Frontiers in neurology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: Migraine is ranked as the third most common and second most disabling neurological disorder worldwide. Neuroimaging studies demonstrate higher white matter lesion (WML) prevalence in migraineurs, with a meta-analysis reporting a 44% pooled prevalence. In the UAE, migraine affects 18.2% of healthcare professionals, but WML prevalence remains unstudied. This study investigates WML prevalence and clinical correlates in UAE migraine patients. Methods: This retrospective study included 313 migraine patients aged 10-50 years who underwent brain MRI at HMS Mirdif Hospital (2022-2025). MRI scans (3T, T2/FLAIR) were assessed by three trained doctors supervised by a radiologist. Demographic, clinical, and MRI data were collected from electronic records. Non-parametric tests and binary logistic regression were used ( Results: A total of 313 migraine patients (median age 32 years, 73.8% female) were included. White matter lesions were identified in 35.5% ( Conclusion: This study found white matter lesions in 35.5% of migraine patients, predominantly affecting frontal and cortical-subcortical regions. Age was the strongest predictor of lesion presence but did not correlate with lesion number. Why WMLs develop in some patients but not others remain unclear. The retrospective single-center design, potential selection bias, limited generalizability, and lack of an age- and sex-matched control group warrant cautious interpretation and underscore the need for prospective studies.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.