ArticleFrontiers in cellular and infection microbiology2026
Genomic epidemiology and phylogenomics of
Article in Frontiers in cellular and infection microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Methods: In this study, we provide the most comprehensive phylogenomic framework to date for this species by analyzing a dataset of 62 whole-genome sequences, including four novel genomes from clinical and environmental strains recovered in a large hospital in southern Italy. Results: Using a pangenome graph-based variant calling strategy on 1,624 high-quality single nucleotide polymorphisms, we delineated eight genetically distinct clades (A-H) that accurately reflect the geo-epidemiological history of this fungus. Population structure analysis revealed significant genetic differentiation among geographically separated populations, suggesting localized diversification. Furthermore, only the Conclusions: This work provides a robust, high-resolution framework for future genomic epidemiology studies and outbreak investigations of this important emerging fungal pathogen.
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