ArticleFrontiers in bioengineering and biotechnology2026
Beyond enzyme engineering: ordered enzyme immobilization drives enhanced productivity
Matthew Wong, Thomas G Neuman, Md Anarul Hoque, Sarah Moraïs, Edward Bayer, Georges Belfort, Mattheos Koffas
Abstract read
In one paragraphArticle in Frontiers in bioengineering and biotechnology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
7 authors.
Matthew Wong *Howard P. Isermann Department of Chemical and Biological Engineering and the Center for Biotechnology and Interdisciplinary Studies, Rensselaer Polytechnic Institute, Troy, NY, United States.
Thomas G Neuman *Howard P. Isermann Department of Chemical and Biological Engineering and the Center for Biotechnology and Interdisciplinary Studies, Rensselaer Polytechnic Institute, Troy, NY, United States.
Md Anarul HoqueHoward P. Isermann Department of Chemical and Biological Engineering and the Center for Biotechnology and Interdisciplinary Studies, Rensselaer Polytechnic Institute, Troy, NY, United States.
Sarah MoraïsFaculty of Natural Sciences, Life Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel.
Edward BayerFaculty of Natural Sciences, Life Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel.
Georges BelfortHoward P. Isermann Department of Chemical and Biological Engineering and the Center for Biotechnology and Interdisciplinary Studies, Rensselaer Polytechnic Institute, Troy, NY, United States.
Mattheos KoffasHoward P. Isermann Department of Chemical and Biological Engineering and the Center for Biotechnology and Interdisciplinary Studies, Rensselaer Polytechnic Institute, Troy, NY, United States.
Funding
Modular and Project Based Training to Enhance Rigor and Reproducibility in Research for Diverse Biomedical CareersT32GM067545 · NIGMS · RENSSELAER POLYTECHNIC INSTITUTE · PI VASHISHTH, DEEPAK · 2004 to 2020
$3.0MBiomolecular Science and Engineering Training Program at Rensselaer Polytechnic InstituteT32GM141865 · NIGMS · RENSSELAER POLYTECHNIC INSTITUTE · PI Blanca Barquera, JUERGEN HAHN · 2021 to 2026
$2.5MNIGMS NIH HHS T32 GM067545NIGMS NIH HHS T32 GM141865
6 · The paper itselfAbstract
Increasing environmental and economic pressures associated with global fossil fuel demand necessitate a shift toward sustainable fuel production. Production of second-generation biofuels, such as isobutanol, presents a promising opportunity; however, product toxicity limits
Indexed as
biofuel synthesiscell freeenhanced enzymatic productivityimmobilized enzymesminimized diffusion limitations
Identifiers
PMID42591215
PMCPMC13461601
What OpenQuestion holds
Textmetadata
LicenceCC BY
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