ArticleFrontiers in medicine2026
Low bacterial contamination rate in platelet components following primary culture screening: a Saudi Arabian experience.
Article in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Platelet storage at room temperature (20-24° C) with agitation facilitates bacterial proliferation. Despite global standards for culture-based screening, there is a lack of component-level contamination data within the Saudi Arabian context. Methods: We conducted a retrospective review of 28,416 post-donation platelet components at the Riyadh regional laboratory (2020-2021) to determine the culture-confirmed bacterial contamination rate. Screening for bacterial contamination utilized the BacT/ALERT Results: Out of 28,416 components, 49 (0.17%) were initially screen-positive. Twenty-five cases were culture-confirmed, yielding a contamination rate of 0.88 per 1,000 components (95% CI: 0.54-1.23) and a Positive Predictive Value (PPV) of 51.0%. Skin commensals predominated, led by Conclusion: The confirmed contamination rate aligns with international benchmarks for primary culture programs. These findings suggest that implementing advanced strategies like Large-Volume Delayed Sampling (LVDS) or near-issue secondary testing could further reduce the residual risk posed by slow-growing skin flora.
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