Evidence map›Paper›PMID 42591107›Full record

ArticleFrontiers in oncology2026

Survival analysis and prognostic factors of mature T-cell and natural killer/T-cell neoplasms in Colombian patients from 2008-2025.

Juan F Combariza-Vallejo, Rocío Orduz-Rodriguez, Natalia Gomez-Lopera, Claudia C Colmenares-Mejia, Liliana Moreno-Martinez, Ana J Salazar-Vargas, Marcela Godoy-Corredor, Mario Arturo Isaza-Ruget

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Article in Frontiers in oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Juan F Combariza-VallejoClínica Colsanitas, Clínica Universitaria Colombia, Bogotá, Colombia.
Rocío Orduz-RodriguezClínica Colsanitas, Laboratorio clínico y de patología, Bogotá, Colombia.
Natalia Gomez-LoperaClínica Colsanitas, Laboratorio clínico y de patología, Bogotá, Colombia.
Claudia C Colmenares-MejiaFundación Universitaria Sanitas, Bogotá, Colombia.
Liliana Moreno-MartinezClínica Colsanitas, Laboratorio clínico y de patología, Bogotá, Colombia.
Ana J Salazar-VargasClínica Colsanitas, Laboratorio clínico y de patología, Bogotá, Colombia.
Marcela Godoy-CorredorClínica Colsanitas, Laboratorio clínico y de patología, Bogotá, Colombia.
Mario Arturo Isaza-RugetClínica Colsanitas, Laboratorio clínico y de patología, Bogotá, Colombia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: T-cell lymphomas show global variation, but research in Latin America remains limited. The main outcome This study aimed to determine, subtype distribution frequency, treatment, and overall survival of T-cell lymphoma. Methods: We conducted a retrospective cohort study of 101 patients with mature T/NK-cell neoplasms (2008-2025). Survival (OS and PFS) was analyzed using Kaplan-Meier estimates and Cox models. Results: Median age was 58 years. PTCL-NOS (31.7%), anaplastic large cell lymphoma (20.8%), and extranodal NK/T-cell lymphoma (18.8%) were the most frequent subtypes. The 36-month OS was 57.8% and PFS was 42.1%. Significant prognostic heterogeneity was observed, with anaplastic large cell lymphoma showing the best and T-prolymphocytic leukemia the poorest outcomes. In multivariable analysis, ECOG status ≥2 independently predicted higher mortality (HR = 2.73, p<0.001), while low LDH levels reduced risk (HR: 0.22; 95% CI: 0.08-0.61; p = 0.003). Conclusions: These findings highlight the marked clinical heterogeneity of T-cell lymphomas and validate the prognostic value of ECOG and LDH in Latin America.

Indexed as

lactate dehydrogenase (LDH)neutrophil to lymphocyte ratio (NLR)progression-free survivalsurvival analysisT-cell lymphoma

Identifiers

PMID42591107
PMCPMC13461328

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.