Evidence map›Paper›PMID 42590000›Full record

ArticleJournal of clinical medicine2026

Clinical Outcomes After Same-Agent Double-Dose Anti-VEGF Escalation in Eyes with a Suboptimal Response to Standard-Dose Treatment for Exudative Macular Diseases: A Real-World Pre-Post Study.

Qiumei Gu, Hongyi Liu, Yifan Xie, Fang Lu, Ziyan He, Yilong Chen, Jiacen Wan, Xiaoshuang Jiang

Abstract read
In one paragraph

Article in Journal of clinical medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Qiumei GuDepartment of Ophthalmology, West China Hospital, Sichuan University, Chengdu 610041, China.ORCID 0009-0000-1940-6121
Hongyi LiuDepartment of Ophthalmology, West China Hospital, Sichuan University, Chengdu 610041, China.ORCID 0009-0004-5208-3423
Yifan XieDepartment of Computer Science, Faculty of Environment, Science and Economy, University of Exeter, Exeter EX4 4RN, UK.ORCID 0009-0003-7250-7759
Fang LuDepartment of Ophthalmology, West China Hospital, Sichuan University, Chengdu 610041, China.
Ziyan HeDepartment of Ophthalmology, West China Hospital, Sichuan University, Chengdu 610041, China.
Yilong ChenWest China Biomedical Big Data Center, West China Hospital, Sichuan University, Chengdu 610041, China.ORCID 0000-0002-5127-2247
Jiacen WanDepartment of Ophthalmology, West China Hospital, Sichuan University, Chengdu 610041, China.
Xiaoshuang JiangDepartment of Ophthalmology, West China Hospital, Sichuan University, Chengdu 610041, China.ORCID 0000-0002-8401-6645

Funding

China Health Promotion Foundation 2025-TYSP-0592Natural Science Foundation of the Xizang Autonomous Region XZ202601ZR0079Science and Technology Department of Sichuan Province 2023NSFSC1666Sichuan University GYYX24011)
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

anti-VEGFdose escalationexudative macular diseasesreal-world studytreatment intensification

Identifiers

PMID42590000
PMCPMC13466651

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.