Evidence map›Paper›PMID 42589889›Full record

ReviewJournal of clinical medicine2026

Mediators of the Pain-Depression Relationship in Adults with Chronic Pain: A Systematic Review and Exploratory Meta-Analyses.

Michael Tenti, Stefania Proietti, Corrado Fagnani, Emanuela Medda, Letizia Sampaolo, Laura Camoni, Federica Cilenti, Giorgia Varallo, Valentina Malafoglia, William Raffaeli and 1 more

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Journal of clinical medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Michael TentiISAL Foundation-ETS, Institute for Research on Pain, 47921 Rimini, Italy.ORCID 0000-0002-4654-018X
Stefania ProiettiAgea Coordinating Body, 00185 Rome, Italy.
Corrado FagnaniCentre for Behavioural Sciences and Mental Health, Istituto Superiore di Sanità (Italian National Institute of Health), 00161 Rome, Italy.ORCID 0000-0001-5771-7772
Emanuela MeddaCentre for Behavioural Sciences and Mental Health, Istituto Superiore di Sanità (Italian National Institute of Health), 00161 Rome, Italy.ORCID 0000-0003-4837-4549
Letizia SampaoloCentre for Disease Prevention and Health Promotion, Istituto Superiore di Sanità (Italian National Institute of Health), 00161 Rome, Italy.ORCID 0000-0001-5370-0973
Laura CamoniCentre for Behavioural Sciences and Mental Health, Istituto Superiore di Sanità (Italian National Institute of Health), 00161 Rome, Italy.ORCID 0000-0001-9007-6479
Federica CilentiISAL Foundation-ETS, Institute for Research on Pain, 47921 Rimini, Italy.
Giorgia VaralloDepartment of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, 41125 Modena, Italy.
Valentina MalafogliaIRCCS San Raffaele Roma, 00166 Rome, Italy.ORCID 0000-0002-1533-704X
William RaffaeliISAL Foundation-ETS, Institute for Research on Pain, 47921 Rimini, Italy.
Virgilia ToccaceliCentre for Behavioural Sciences and Mental Health, Istituto Superiore di Sanità (Italian National Institute of Health), 00161 Rome, Italy.ORCID 0000-0002-9038-521X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

chronic paindepressiondepressive symptomshelplessnessmediation analysismeta-analysispain catastrophizingpain intensitysystematic review

Identifiers

PMID42589889
PMCPMC13466972

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.