Evidence map›Paper›PMID 42589670›Full record

ArticleInternational journal of molecular sciences2026

Evaluation of HER2 and Nectin-4 Expression in Primary Vaginal Cancers.

Gilbert Georg Klamminger, Hanna Wattendorff, Felix Hässlin, Christoph Eckert, Silke Mitschke, Stefanie Zimmer, Meletios P Nigdelis, Roxana Schwab, Walburgis Brenner, Annette Hasenburg and 1 more

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Gilbert Georg KlammingerDepartment of Obstetrics and Gynecology, University Medical Center of the Johannes Gutenberg University Mainz, 55131 Mainz, Germany.ORCID 0000-0001-5358-2751
Hanna WattendorffInstitute of Pathology, University Medical Center of the Johannes Gutenberg University Mainz, 55131 Mainz, Germany.
Felix HässlinDepartment of Obstetrics and Gynecology, University Medical Center of the Johannes Gutenberg University Mainz, 55131 Mainz, Germany.
Christoph EckertInstitute of Pathology, University Medical Center of the Johannes Gutenberg University Mainz, 55131 Mainz, Germany.
Silke MitschkeInstitute of Pathology, University Medical Center of the Johannes Gutenberg University Mainz, 55131 Mainz, Germany.
Stefanie ZimmerInstitute of Pathology, University Medical Center of the Johannes Gutenberg University Mainz, 55131 Mainz, Germany.
Meletios P NigdelisDepartment of Gynecology, Obstetrics and Reproductive Medicine, Saarland University Medical Center (UKS), 66424 Homburg, Germany.ORCID 0000-0003-3865-6833
Roxana SchwabDepartment of Obstetrics and Gynecology, University Medical Center of the Johannes Gutenberg University Mainz, 55131 Mainz, Germany.ORCID 0000-0002-1489-0011
Walburgis BrennerDepartment of Obstetrics and Gynecology, University Medical Center of the Johannes Gutenberg University Mainz, 55131 Mainz, Germany.ORCID 0000-0002-1511-6212
Annette HasenburgDepartment of Obstetrics and Gynecology, University Medical Center of the Johannes Gutenberg University Mainz, 55131 Mainz, Germany.ORCID 0000-0002-1547-4968
Yaman DegirmenciDepartment of Obstetrics and Gynecology, University Medical Center of the Johannes Gutenberg University Mainz, 55131 Mainz, Germany.ORCID 0000-0002-3713-9490

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study assessed the prevalence and clinical relevance of p16

Indexed as

Cell Adhesion MoleculesErb-b2 Receptor Tyrosine KinasesNectinsVaginal NeoplasmsAdultAgedAged, 80 and overBiomarkers, TumorCyclin-Dependent Kinase Inhibitor p16FemaleHumansImmunohistochemistryMiddle AgedPrognosisTumor Suppressor Protein p53Biomarkers, TumorCell Adhesion MoleculesCyclin-Dependent Kinase Inhibitor p16ERBB2 protein, humanErb-b2 Receptor Tyrosine KinasesNECTIN4 protein, humanNectinsTumor Suppressor Protein p53druggable targetsHER2Nectin-4primary vaginal cancertumor-agnostic therapy

Identifiers

PMID42589670
PMCPMC13467148

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.