Evidence map›Paper›PMID 42589580›Full record

ArticleInternational journal of molecular sciences2026

Prime Editing Mediated Generation and Correction of the mdx5cv Mutation Restores Dystrophin Expression in Myoblasts.

Ayesha Siddika, Fatima El Husseiny, Joël Rousseau, Jacques P Tremblay

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ayesha SiddikaDepartment of Molecular Medicine, Université Laval, Quebec, QC G1V 0A6, Canada.
Fatima El HusseinyDepartment of Molecular Medicine, Université Laval, Quebec, QC G1V 0A6, Canada.
Joël RousseauCHU de Québec Research Center, Université Laval, Quebec, QC G1V 4G2, Canada.
Jacques P TremblayDepartment of Molecular Medicine, Université Laval, Quebec, QC G1V 0A6, Canada.ORCID 0000-0001-9404-9195

Funding

Defeat Duchenne Foundation, Canada 53320215
6 · The paper itself

Abstract

Duchenne muscular dystrophy (DMD) is caused by mutations in the

Indexed as

DystrophinGene EditingMuscular Dystrophy, DuchenneMutationMyoblastsAnimalsCell LineCRISPR-Cas SystemsMiceRNA, Guide, CRISPR-Cas SystemsDystrophinRNA, Guide, CRISPR-Cas SystemsDmd geneDuchenne muscular dystrophydystrophingenome editingmdx5cvmyoblastspoint mutationprime editing

Identifiers

PMID42589580
PMCPMC13467296

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.