Evidence map›Paper›PMID 42589534›Full record

ArticleInternational journal of molecular sciences2026

Antimicrobial Properties of Freeze-Dried Hyaluronic Acid Sheets Containing Persimmon Tannin.

Yasuhisa Sawai, Miho Hasumoto, Takanobu Takata, Arina Nakamichi, Mahmoud Gallab, Kunio Yoneto, Chika Yoneto, Satoshi Wada, Eiji Mitate, Seiji Yamaguchi and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Yasuhisa SawaiDepartment of Oral and Maxillofacial Surgery, Faculty of Medicine, Kanazawa Medical University, Kahoku 920-0293, Japan.ORCID 0009-0005-2428-3417
Miho HasumotoDepartment of Oral and Maxillofacial Surgery, Faculty of Medicine, Kanazawa Medical University, Kahoku 920-0293, Japan.
Takanobu TakataDepartment of Pathology II, Faculty of Medicine, Kanazawa Medical University, Kahoku 920-0293, Japan.ORCID 0000-0003-0514-8584
Arina NakamichiDepartment of Oral and Maxillofacial Surgery, Faculty of Medicine, Kanazawa Medical University, Kahoku 920-0293, Japan.
Mahmoud GallabDepartment of Biomedical Sciences, College of Life and Health Sciences, Chubu University, Kasugai 487-0027, Japan.
Kunio YonetoRitapharma, Co., Ltd., Kyoto 600-8813, Japan.
Chika YonetoRitapharma, Co., Ltd., Kyoto 600-8813, Japan.
Satoshi WadaDepartment of Oral and Maxillofacial Surgery, Faculty of Medicine, Kanazawa Medical University, Kahoku 920-0293, Japan.
Eiji MitateDepartment of Oral and Maxillofacial Surgery, Faculty of Medicine, Kanazawa Medical University, Kahoku 920-0293, Japan.
Seiji YamaguchiDepartment of Biomedical Sciences, College of Life and Health Sciences, Chubu University, Kasugai 487-0027, Japan.
Hiroyuki NakanoDepartment of Oral and Maxillofacial Surgery, Faculty of Medicine, Kanazawa Medical University, Kahoku 920-0293, Japan.ORCID 0000-0002-0532-1853

Funding

Japan Society for the Promotion of Science JP24K14802Japan Society for the Promotion of Science JP25K20422
6 · The paper itself

Abstract

Oral mucositis is a frequent adverse effect of cancer therapy and is often complicated by pain, oral dryness, and secondary infection. Freeze-dried hyaluronic acid (HA) sheets can protect and moisturize the oral mucosa, but their intrinsic antibacterial activity is limited. We developed freeze-dried HA sheets containing the commercial persimmon tannin product PANCIL

Indexed as

Anti-Infective AgentsDiospyrosHyaluronic AcidTanninsCandida albicansCell LineCell SurvivalFreeze DryingHumansMicrobial Sensitivity TestsAnti-Infective AgentsHyaluronic AcidTanninsantibacterial activityhyaluronic acidoral mucositispersimmon tannin

Identifiers

PMID42589534
PMCPMC13467313

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.