Evidence map›Paper›PMID 42589351›Full record

ArticleInternational journal of molecular sciences2026

Glycyrrhizic Acid Alleviates Atherosclerosis in

Haoran Shen, Shuai Huang, Zhiyu Wang, Sitong Zhou, Lulu Huang, Hongjuan Zhang, Yanxing Han, Jiandong Jiang, Huihui Guo

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Haoran ShenState Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100050, China.
Shuai HuangBiomedical Innovation Center, Beijing Shijitan Hospital, Capital Medical University, Beijing 100038, China.
Zhiyu WangState Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100050, China.
Sitong ZhouState Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100050, China.
Lulu HuangHubrecht Institute, Royal Netherlands Academy of Arts and Sciences (KNAW) and University Medical Center Utrecht, 3584 Utrecht, The Netherlands.
Hongjuan ZhangState Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100050, China.
Yanxing HanState Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100050, China.ORCID 0000-0003-0073-4357
Jiandong JiangState Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100050, China.
Huihui GuoState Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100050, China.

Funding

CAMS Innovation Fund for Medical Sciences No. 2025-I2M-KJ-016Fundamental Research Funds for the Central Universities No. 3332025150
6 · The paper itself

Abstract

Glycyrrhizic acid (GL), a natural triterpenoid glycoside extracted from the "medicine food homology" herb

Indexed as

Apolipoproteins EAtherosclerosisGlycyrrhizic AcidIndolesReceptors, Aryl HydrocarbonTranscription Factor RelAAnimalsDiet, High-FatEndothelium, VascularFecal Microbiota TransplantationGastrointestinal MicrobiomeHumansMaleMiceMice, Inbred C57BLMice, KnockoutApolipoproteins EGlycyrrhizic Acidindole-3-lactic acidIndolesReceptors, Aryl HydrocarbonTranscription Factor RelAatherosclerosisendothelial inflammationglycyrrhizic acidindole-3-lactic acidmicrobiota–vascular axis

Identifiers

PMID42589351
PMCPMC13467423

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.