Molecular Characterization and Genetic Significance of a Rare Type-I Triallelic Pattern Involving a 15.3 Microvariant at the D19S433 Locus.

Vera Djeliova, Stanislava Dimitrova-Nikolova, Tzanko Markov, Yanko Kolev, Atanas Hristov, Milka Mileva, Aleksandar Apostolov

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Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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7 authors.

Vera DjeliovaDepartment of the Molecular Biology of the Cell Cycle, Institute of Molecular Biology Acad. Rumen Tsanev, Bulgarian Academy of Sciences, "Acad. G. Bonchev" Street, Bl. 21, 1113 Sofia, Bulgaria.ORCID 0000-0002-0095-8046

Stanislava Dimitrova-NikolovaDNA Laboratory, National Institute of Forensics, Bul. Alexander Malinov 1, 1756 Sofia, Bulgaria.

Tzanko MarkovDNA Laboratory, National Institute of Forensics, Bul. Alexander Malinov 1, 1756 Sofia, Bulgaria.

Yanko KolevDepartment of Forensic Medicine, Multidisciplinary Hospital for Active Treatment "Gabrovo" District Hospital, 5300 Gabrovo, Bulgaria.ORCID 0000-0003-2958-1702

Atanas HristovClinic of Forensic Medicine and Deontology, University Hospital Alexandrovska, 1 St. Georg Sofiiski Blvd., 1431 Sofia, Bulgaria.

Milka MilevaDepartment of Virology, Institute of Microbiology, Bulgarian Academy of Sciences, 26 Acad. G. Bonchev Str, 1113 Sofia, Bulgaria.ORCID 0000-0002-3218-4487

Aleksandar ApostolovClinic of Forensic Medicine and Deontology, University Hospital Alexandrovska, 1 St. Georg Sofiiski Blvd., 1431 Sofia, Bulgaria.ORCID 0000-0002-5214-4714

Funding

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6 · The paper itself

Abstract

Short tandem repeat (STR) analysis is the main reference standard in forensic genetics. Despite its reliability, rare genetic anomalies like triallelic patterns and microvariants challenge profile interpretation. This study characterizes an exceptional genetic finding identified during routine casework at the Research Institute of Forensic Science in Sofia, Bulgaria. DNA was isolated from dental remains of an unidentified male corpse and amplified using the Investigator

Indexed as

Forensic GeneticsGenetic LociMicrosatellite RepeatsAllelesBulgariaGenotypeHumansMaleSegmental Duplications, GenomicBulgarian populationD19S433microvariant 15.3STR profilingtriallelic pattern

Identifiers

PMID42589279

DOI10.3390/ijms27156621

PMCPMC13466694

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