Evidence map›Paper›PMID 42589266›Full record

ArticleInternational journal of molecular sciences2026

Analysis of Matrix Metalloproteinase-8 Gene Polymorphisms and Their Association with Long-Term Survival, Clinical Phenotype, and Disease Risk in Patients with Coronary Artery Disease.

Justyna Wrona, Anna Balcerzyk-Matić, Tomasz Nowak, Katarzyna Mizia-Stec, Artur Filipecki, Jolanta Krauze, Paweł Niemiec

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Justyna WronaDepartment of Biochemistry and Medical Genetics, Faculty of Health Sciences in Katowice, Medical University of Silesia, Medykow Street 18, 40-752 Katowice, Poland.ORCID 0009-0001-5508-8076
Anna Balcerzyk-MatićDepartment of Biochemistry and Medical Genetics, Faculty of Health Sciences in Katowice, Medical University of Silesia, Medykow Street 18, 40-752 Katowice, Poland.ORCID 0000-0002-1113-7796
Tomasz NowakDepartment of Biochemistry and Medical Genetics, Faculty of Health Sciences in Katowice, Medical University of Silesia, Medykow Street 18, 40-752 Katowice, Poland.ORCID 0000-0002-6712-5911
Katarzyna Mizia-StecFirst Department of Cardiology, Faculty of Medical Sciences in Katowice, Medical University of Silesia, Ziolowa Street 47, 40-635 Katowice, Poland.ORCID 0000-0001-6907-2799
Artur FilipeckiFirst Department of Cardiology, Faculty of Medical Sciences in Katowice, Medical University of Silesia, Ziolowa Street 47, 40-635 Katowice, Poland.
Jolanta Krauze1st Department of Cardiac Surgery/2nd Department of Cardiology, American Heart of Poland, S. A. Armii Krajowej Street 101, 43-316 Bielsko-Biala, Poland.
Paweł NiemiecDepartment of Biochemistry and Medical Genetics, Faculty of Health Sciences in Katowice, Medical University of Silesia, Medykow Street 18, 40-752 Katowice, Poland.

Funding

Medical University of Silesia BNW-1-068/N/5/Z
6 · The paper itself

Abstract

Matrix metalloproteinase-8 (MMP-8), a neutrophil-derived collagenase responsible for the degradation of type I and III collagen, is involved in extracellular matrix remodeling, which may contribute to the destabilization of atherosclerotic plaques and thereby promote the development and progression of coronary artery disease (CAD). Single-nucleotide polymorphisms (SNPs) in the

Indexed as

Coronary Artery DiseaseGenetic Predisposition to DiseaseMatrix Metalloproteinase 8Polymorphism, Single NucleotideAgedAllelesFemaleGenetic Association StudiesGenotypeHaplotypesHumansMaleMiddle AgedPhenotypePrognosisRisk FactorsMatrix Metalloproteinase 8MMP8 protein, humancoronary artery diseaselong-term survivalMMP-8polymorphisms

Identifiers

PMID42589266
PMCPMC13466682

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.