Evidence map›Paper›PMID 42589094›Full record

ArticleBiology2026

Evaluation of the In Vivo Antioxidant Capacity of Sheep Hemoglobin Hydrolysate in a Rat Model.

Yina Qiao, Zhenru Wang, Yilin Yang, Yang Zi, Mingyue Li, Xin Hou, Yingchun Liu, Yujie Guo, Feng Gao

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yina QiaoCollege of Animal Science, Inner Mongolia Agricultural University, Hohhot 010018, China.ORCID 0000-0002-8703-6481
Zhenru WangCollege of Animal Science, Inner Mongolia Agricultural University, Hohhot 010018, China.
Yilin YangCollege of Animal Science, Inner Mongolia Agricultural University, Hohhot 010018, China.
Yang ZiCollege of Animal Science, Inner Mongolia Agricultural University, Hohhot 010018, China.
Mingyue LiCollege of Animal Science, Inner Mongolia Agricultural University, Hohhot 010018, China.
Xin HouCollege of Animal Science, Inner Mongolia Agricultural University, Hohhot 010018, China.
Yingchun LiuInner Mongolia Key Laboratory of Biomanufacturing, College of Life Science, Inner Mongolia Agricultural University, Hohhot 010011, China.
Yujie GuoKey Laboratory of Agro-Products Processing, Ministry of Agriculture and Rural Affairs, Institute of Food Science and Technology, Chinese Academy of Agricultural Sciences, Beijing 100193, China.
Feng GaoCollege of Animal Science, Inner Mongolia Agricultural University, Hohhot 010018, China.ORCID 0000-0002-4461-6611

Funding

China Agriculture Research System of MOF and MARA CARS-38Interdisciplinary Research Fund of Inner Mongolia Agricultural University BRS231402Science and Technology Plan Project of Inner Mongolia Autonomous Region 2023YFHH0030
6 · The paper itself

Abstract

Sheep hemoglobin hydrolysate (SHH) has important biological antioxidant functions. However, the specific mechanism is not well understood. The aim of this study was to investigate the antioxidant activity of SHH in vivo and its potential mechanism. Eighteen Sprague Dawley rats were randomly divided into DG (gavaged with 0.9% saline), VC (gavaged with vitamin C 100 mg/kg BW) and SHH (gavaged with SHH 800 mg/kg BW) groups. The rats were given intragastric administration for 21 days. On the 22nd day, all rats were intraperitoneally injected with diquat as a challenge. The results showed that SHH treatment had no obvious effect on the growth performance and main organ index of rats after the diquat challenge. Compared to the DG group, the SHH group maintained higher serum T-AOC and GSH-Px levels after the diquat challenge. SHH significantly increased GSH-Px activity in the liver and kidney, and decreased MDA content in the kidney after the diquat challenge. SHH significantly up-regulated the gene expression of

Indexed as

antioxidant functionenzymatic hydrolysateNF-κBNrf2-AREratsheep hemoglobin

Identifiers

PMID42589094
PMCPMC13464934

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.