In Situ Construction of Fascial Analogues Induced by Low-Growth-Factor Matrigel.

Jianming Yue, Yumeng Guo, Haixiang Huang, Zhenwei Zhang, Lu Mei, Qiusheng Chen

Abstract read

In one paragraph

Article in Animals : an open access journal from MDPI, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jianming YueMOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing 210095, China.

Yumeng GuoMOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing 210095, China.

Haixiang HuangMOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing 210095, China.

Zhenwei ZhangMOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing 210095, China.

Lu MeiMOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing 210095, China.

Qiusheng ChenMOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing 210095, China.ORCID 0000-0002-6087-7029

Funding

National Natural Science Foundation of China 31872433

6 · The paper itself

Abstract

Fascia serves as both a mechanical scaffold and a progenitor cell reservoir critical for wound healing and tissue regeneration. This study developed an In Situ Induced Fascial Analogue (iFA) via low-growth-factor Matrigel injection into mouse subcutaneous fascia, using silicone as a control. At 14 days, histological and ultrastructural analyses showed that the iFA possessed an organized collagen architecture comparable to native fascia, distinct from the dense fibrous capsules in controls. qPCR and immunofluorescence revealed a pro-reparative macrophage-associated microenvironment characterized by increased CD206 expression and demonstrated the enrichment of CD34

Indexed as

fascialmacrophageMatrigelTelocytestissue engineering

Identifiers

PMID42588924

DOI10.3390/ani16152287

PMCPMC13463716

What OpenQuestion holds

Textmetadata

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.