The Multidrug Resistance Protein OsMDR4 Is Involved in Cadmium Absorption in Rice (

Zijing Xie, Xiaohua Hao, Dan Zhao, Han Lei, Xinzhou Jin, Sha Wu, Wenli Hu, Lianfu Tian, Dongping Li

Abstract read

In one paragraph

Article in Plants (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Zijing XieHunan Provincial Key Laboratory of the Traditional Chinese Medicine Agricultural Biogenomics, Changsha Medical University, Changsha 410219, China.ORCID 0009-0005-7402-0359

Xiaohua HaoHunan Province Key Laboratory of Crop Sterile Germplasm Resource Innovation and Application, College of Life Sciences, Hunan Normal University, Changsha 410081, China.

Dan ZhaoHunan Province Key Laboratory of Crop Sterile Germplasm Resource Innovation and Application, College of Life Sciences, Hunan Normal University, Changsha 410081, China.

Han LeiHunan Province Key Laboratory of Crop Sterile Germplasm Resource Innovation and Application, College of Life Sciences, Hunan Normal University, Changsha 410081, China.

Xinzhou JinHunan Province Key Laboratory of Crop Sterile Germplasm Resource Innovation and Application, College of Life Sciences, Hunan Normal University, Changsha 410081, China.

Sha WuHunan Province Key Laboratory of Crop Sterile Germplasm Resource Innovation and Application, College of Life Sciences, Hunan Normal University, Changsha 410081, China.

Wenli HuHunan Province Key Laboratory of Crop Sterile Germplasm Resource Innovation and Application, College of Life Sciences, Hunan Normal University, Changsha 410081, China.

Lianfu TianHunan Province Key Laboratory of Crop Sterile Germplasm Resource Innovation and Application, College of Life Sciences, Hunan Normal University, Changsha 410081, China.

Dongping LiHunan Province Key Laboratory of Crop Sterile Germplasm Resource Innovation and Application, College of Life Sciences, Hunan Normal University, Changsha 410081, China.

Funding

Changsha Municipal Natural Science Foundation kq2014076Hunan Natural Science Foundation 2021JJ30445Hunan Natural Science Foundation 2022JJ30421Hunan Provincial Innovation Foundation for Postgraduates CX20200530Hunan Provincial Innovation Foundation for Postgraduates CX20220515Key Project of Developmental Biology and Breeding from Hunan Province 2000XKQ0203National Natural Science Foundation of China 32071930Scientific Research Foundation of Hunan Provincial Education Department 24B0887

6 · The paper itself

Abstract

Cadmium (Cd) is a toxic metal that poses a significant threat to crop production and global food security. Transporters play a critical role in mediating the uptake of metal ions, including Cd. However, a substantial number of Cd transporters in rice remain uncharacterized. In this study, we identify OsMDR4, a member of the multidrug resistance protein family, as a mediator of Cd uptake in rice. Heterologous overexpression of OsMDR4 in yeast increased both Cd sensitivity and intracellular Cd accumulation. Consistent with this, the Cd concentrations in both roots and shoots of the

Indexed as

ABC transportercadmium accumulationOsMDR4rice

Identifiers

PMID42588881

DOI10.3390/plants15152378

PMCPMC13468201

What OpenQuestion holds

Textmetadata

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.