ArticleMolecules (Basel, Switzerland)2026
Biological Profile of Ferulic Acid-Based Thiazolidin-4-One Derivatives: Toxicity, Inflammation, and Oxidative Stress Biomarkers.
Maria Dragan, Andreea-Teodora Iacob, Cornelia Mircea, Catalina Daniela Stan, Oana-Maria Dragostin, Alin-Viorel Focșa, Diana Tatarciuc, Ruxandra-Teodora Stan, Mihaela Poroch, Lenuta Profire
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In one paragraphArticle in Molecules (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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What it found
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2 · The registryThe trial behind it
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5 · Who and what moneyAuthors and funding
10 authors.
Maria DraganDepartment of Pharmaceutical Sciences II, Faculty of Pharmacy, Grigore T. Popa University of Medicine and Pharmacy Iasi, 16 University Street, 700115 Iasi, Romania.ORCID 0000-0002-9138-1843 Andreea-Teodora IacobDepartment of Pharmaceutical Sciences I, Faculty of Pharmacy, Grigore T. Popa University of Medicine and Pharmacy Iasi, 16 University Street, 700115 Iasi, Romania.ORCID 0000-0003-2530-3801 Cornelia MirceaDepartment of Pharmaceutical Sciences II, Faculty of Pharmacy, Grigore T. Popa University of Medicine and Pharmacy Iasi, 16 University Street, 700115 Iasi, Romania.ORCID 0000-0002-1981-8246 Catalina Daniela StanDepartment of Pharmaceutical Sciences II, Faculty of Pharmacy, Grigore T. Popa University of Medicine and Pharmacy Iasi, 16 University Street, 700115 Iasi, Romania.ORCID 0000-0003-0132-2442 Oana-Maria DragostinResearch Centre in the Medical-Pharmaceutical Field, Faculty of Medicine and Pharmacy, "Dunărea de Jos" University of Galati, 800201 Galati, Romania.ORCID 0000-0002-0389-8974 Alin-Viorel FocșaDepartment of Pharmaceutical Sciences II, Faculty of Pharmacy, Grigore T. Popa University of Medicine and Pharmacy Iasi, 16 University Street, 700115 Iasi, Romania.ORCID 0009-0000-3963-8376 Diana TatarciucDepartment of Internal Medicine I, Faculty of Medicine, Grigore T. Popa University of Medicine and Pharmacy Iasi, 16 University Street, 700115 Iasi, Romania.
Ruxandra-Teodora StanDepartment of Implantology, Removable Prosthodontics and Dental Technology, Faculty of Dental Medicine, Grigore T. Popa University of Medicine and Pharmacy Iasi, 16 University Street, 700115 Iasi, Romania.
Mihaela PorochDepartment of Preventive Medicine and Interdisciplinarity, Faculty of Medicine, Grigore T. Popa University of Medicine and Pharmacy Iasi, 16 University Street, 700115 Iasi, Romania.ORCID 0000-0003-0370-2748 Lenuta ProfireDepartment of Pharmaceutical Sciences I, Faculty of Pharmacy, Grigore T. Popa University of Medicine and Pharmacy Iasi, 16 University Street, 700115 Iasi, Romania.ORCID 0000-0002-7953-3023 Funding
No grant is acknowledged in the PubMed record.
6 · The paper itselfAbstract
Since inflammation is a fundamental process involved in tissue injury and repair, the evaluation of the anti-inflammatory potential of novel compounds is of considerable importance. Acute toxicity evaluation in Swiss albino mice revealed that the synthesized thiazolidin-4-one derivatives of ferulic acid possess moderate toxicity. The in vivo biological activity of synthesized thiazolidin-4-one derivatives (
Indexed as
Anti-Inflammatory AgentsCoumaric AcidsInflammationOxidative StressThiazolidinesAnimalsBiomarkersCarrageenanEdemaMaleMiceRatsAnti-Inflammatory AgentsBiomarkersCarrageenanCoumaric Acidsferulic acidThiazolidinesanti-inflammatory actionferulic acid derivativesthiazolidin-4-onetoxicity determination
Identifiers
PMID42588495
PMCPMC13468139
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