Evidence map›Paper›PMID 42588480›Full record

ArticleMolecules (Basel, Switzerland)2026

Sustainable Active Packaging Based on Chitosan-Pomegranate Peel Biofilm Protects Pecorino Romano PDO Cheese Through Polyphenol-Driven Antioxidant and Antimicrobial Activity.

Sara Palmieri, Valentina Mangano, Elisa Capini, Giulia De Grazia, Giovanna Loredana La Torre, Federico Fanti, Manuel Sergi, Andrea Salvo

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Sara PalmieriDepartment of Biosciences and Technologies for Agriculture, Food and Environment, University of Teramo, Via Balzarini 1, 64100 Teramo, Italy.ORCID 0000-0003-4671-7261
Valentina ManganoAEDES S.r.l., Via Cancelliera 12, 00041 Albano Laziale, Italy.
Elisa CapiniAEDES S.r.l., Via Cancelliera 12, 00041 Albano Laziale, Italy.
Giulia De GraziaAEDES S.r.l., Via Cancelliera 12, 00041 Albano Laziale, Italy.
Giovanna Loredana La TorreDepartment of Biomedical and Dental Sciences and Morpho-Functional Imaging, University of Messina, Polo Universitario Annunziata, Viale Annunziata, 98168 Messina, Italy.ORCID 0000-0001-6304-6899
Federico FantiDepartment of Biosciences and Technologies for Agriculture, Food and Environment, University of Teramo, Via Balzarini 1, 64100 Teramo, Italy.ORCID 0000-0002-9235-5874
Manuel SergiDepartment of Chemistry and Drug Technology, University of Rome La Sapienza, Via P. le A. Moro 5, 00185 Roma, Italy.
Andrea SalvoDepartment of Chemistry and Drug Technology, University of Rome La Sapienza, Via P. le A. Moro 5, 00185 Roma, Italy.ORCID 0000-0002-0519-5084

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A chitosan-based edible biofilm enriched with pomegranate peel extract and essential oils was developed as a sustainable active packaging material that exploits agro-industrial by-products, in agreement with circular economy principles. Targeted HPLC-MS/MS analysis quantified twelve polyphenols, with total polyphenol content ranging from 88.20 to 137.38 μg/g dry weight. Ellagic acid was the predominant compound (90.78 μg/g dry weight), followed by gallic acid (28.80 μg/g dry weight). Untargeted HPLC-HRMS analysis revealed additional flavonoid and ellagitannin-related derivatives, confirming the chemical complexity of the incorporated phenolic fraction. ICP-OES analysis showed heavy metal concentrations below the analytical quantification limits, supporting compliance with food-contact safety requirements. During 45 days of refrigerated storage, coated Pecorino Romano PDO cheese exhibited lower yeast and mold counts than uncoated controls, with a maximum reduction of approximately 0.87 log

Indexed as

Anti-Infective AgentsAntioxidantsBiofilmsCheeseChitosanFood PackagingPolyphenolsPomegranateChromatography, High Pressure LiquidPlant ExtractsAnti-Infective AgentsAntioxidantsChitosanPlant ExtractsPolyphenolsactive packagingchitosanedible biofilmfood safetypolyphenolspomegranate peelshelf-life

Identifiers

PMID42588480
PMCPMC13468628

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.