ArticleMolecules (Basel, Switzerland)2026
Chemical Profiling and Differential Constituents Analysis of Honghema and Its Easily Confusable Species Driven by High-Resolution Mass Spectrometry and Pattern Recognition.
Congying Huang, Yute Zhong, Han Li, Dan Wu, Taiping Li, Weijie Li, Siying Chen, Zipeng Gong, Haiyu Xu, Ping Wang
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In one paragraphArticle in Molecules (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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10 authors.
Congying HuangState Key Laboratory for Quality Ensurance and Sustainable Use of Dao-di Herbs, Institute of Chinese Materia Medica China Academy of Chinese Medical Sciences, Beijing 100700, China.ORCID 0009-0001-9718-2714 Yute ZhongState Key Laboratory for Quality Ensurance and Sustainable Use of Dao-di Herbs, Institute of Chinese Materia Medica China Academy of Chinese Medical Sciences, Beijing 100700, China.
Han LiState Key Laboratory for Quality Ensurance and Sustainable Use of Dao-di Herbs, Institute of Chinese Materia Medica China Academy of Chinese Medical Sciences, Beijing 100700, China.
Dan WuState Key Laboratory for Quality Ensurance and Sustainable Use of Dao-di Herbs, Institute of Chinese Materia Medica China Academy of Chinese Medical Sciences, Beijing 100700, China.
Taiping LiLiaoning University of Traditional Chinese Medicine, Shenyang 117004, China.
Weijie LiState Key Laboratory for Quality Ensurance and Sustainable Use of Dao-di Herbs, Institute of Chinese Materia Medica China Academy of Chinese Medical Sciences, Beijing 100700, China.
Siying ChenState Key Laboratory of Discovery and Utilization of Functional Components in Traditional Chinese Medicine, Engineering Research Center for the Development and Application of Ethnic Medicine and TCM (Ministry of Education), School of Pharmacy, Guizhou Medical University, Guian New Area 561113, China.
Zipeng GongState Key Laboratory of Discovery and Utilization of Functional Components in Traditional Chinese Medicine, Engineering Research Center for the Development and Application of Ethnic Medicine and TCM (Ministry of Education), School of Pharmacy, Guizhou Medical University, Guian New Area 561113, China.ORCID 0000-0003-2074-9476 Haiyu XuLiaoning University of Traditional Chinese Medicine, Shenyang 117004, China.
Ping WangState Key Laboratory for Quality Ensurance and Sustainable Use of Dao-di Herbs, Institute of Chinese Materia Medica China Academy of Chinese Medical Sciences, Beijing 100700, China.
Funding
Excellent Young Talents Plan of Guizhou Province QKHPTRC-YQK[2023]029Fundamental Research Funds for the Central public welfare research institutes ZXKT25041National Natural Science Foundation of China 82360815National Natural Science Foundation of China 82574682National Natural Science Foundation of China U25A20167Natural Science Foundation of Guizhou Province Qian Ke He Ji Chu-ZK[2024] Zhong Dian 049, Qian Ke He Ji Chu QNA[2025]002Natural Science Research Foundation of Guizhou Provincial Department of Education Qian Jiao Ji[2023]066
6 · The paper itselfAbstract
backgroundHonghema is a traditional Chinese medicinal material and is also widely used by ethnic minority communities in Guizhou Province, where it is commonly known as "Reib ndad gunb" and "Uab Detdend". The botanical origins were the whole plants of
methodsData acquisition was performed using ultra-performance liquid chromatography-mass spectrometry (UPLC-MS). Multivariate statistical analyses combined with reference standard comparison were performed to investigate the differences in chemical profiles among
resultsA total of 133, 77, and 59 chemical constituents were identified from
conclusionSignificant differences were observed among the chemical profiles of the three plant species. The method established in this study can effectively identify the chemical compositions of Honghema and its easily confusable species, revealing the key components responsible for the variations in their chemical profiles. This study provides a basis for elucidating the material foundation of Honghema and offers an effective analytical approach and valuable reference data for distinguishing Honghema from its easily confusable species.
Indexed as
Drugs, Chinese HerbalPlant ExtractsUrticaceaeChromatography, High Pressure LiquidLiquid Chromatography-Mass SpectrometryMass SpectrometryDrugs, Chinese HerbalPlant Extractschemical profilingdifferential constituentsGirardinia diversifolia (Link) FriisHonghemaLaportea bulbifera (Siebold &UPLC-Q-TOF-MS/MSUrtica mairei H. Lév.Zucc.) Wedd.
Identifiers
PMID42588463
PMCPMC13468369
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