Evidence map›Paper›PMID 42588411›Full record

ArticleMolecules (Basel, Switzerland)2026

Ginsenoside Rg1 Alleviates Lead-Induced Neurotoxicity Through Nrf2-Associated Modulation of Oxidative Stress and Ferroptosis.

Yiyao Gong, Jie Zhang, Tingting Wang, Xiang Li, Hao Wang, Li Ren

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yiyao GongCollege of Food Science and Engineering, Jilin University, Changchun 130062, China.
Jie ZhangCollege of Food Science and Engineering, Jilin University, Changchun 130062, China.ORCID 0000-0002-6944-2021
Tingting WangCollege of Food Science and Engineering, Jilin University, Changchun 130062, China.
Xiang LiCollege of Basic Medical Sciences, Jilin University, Changchun 130021, China.ORCID 0000-0001-7026-3795
Hao WangAdvanced Medical Research Institute, Shandong University, Jinan 250012, China.
Li RenCollege of Food Science and Engineering, Jilin University, Changchun 130062, China.ORCID 0000-0002-0564-4265

Funding

Jilin University X202610183270Shandong University ts20250105
6 · The paper itself

Abstract

Chronic exposure to lead (Pb) represents a persistent environmental hazard that can impair hippocampal integrity and cognitive function, while effective protective strategies remain limited. Ginsenoside Rg1 is an important bioactive constituent derived from

Indexed as

FerroptosisGinsenosidesLeadNeuroprotective AgentsNeurotoxicity SyndromesNF-E2-Related Factor 2Oxidative StressAnimalsAntioxidantsCell LineHippocampusMaleMiceMice, Inbred C57BLNeuronsSignal TransductionAntioxidantsginsenoside Rg1GinsenosidesLeadNeuroprotective AgentsNfe2l2 protein, mouseNF-E2-Related Factor 2ferroptosisginsenoside Rg1lead neurotoxicityoxidative stress

Identifiers

PMID42588411
PMCPMC13468199

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.