Evidence map›Paper›PMID 42588119›Full record

ReviewNutrients2026

From Diet to Dysbiosis: How Nutritional Factors Shape Gut Microbiota and Drive Airway Inflammation in Pediatric Asthma.

Oana Raluca Temneanu, Adriana Mihai, Raluca Olariu, Mihaela Oros, Ileana Ioniuc, Vasile Valeriu Lupu, Ancuța Lupu, Alice Grudnicki, Manuel Florin Roșu, Roxana Șerban and 2 more

Abstract readReview
In one paragraph

Review in Nutrients, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Oana Raluca TemneanuGrigore T. Popa University of Medicine and Pharmacy, 700115 Iași, Romania.ORCID 0009-0006-2791-5165
Adriana MihaiGrigore T. Popa University of Medicine and Pharmacy, 700115 Iași, Romania.ORCID 0009-0007-6133-8784
Raluca OlariuGrigore T. Popa University of Medicine and Pharmacy, 700115 Iași, Romania.ORCID 0009-0001-1221-5397
Mihaela OrosTitu Maiorescu University, 031593 Bucharest, Romania.ORCID 0000-0002-9470-8880
Ileana IoniucGrigore T. Popa University of Medicine and Pharmacy, 700115 Iași, Romania.
Vasile Valeriu LupuGrigore T. Popa University of Medicine and Pharmacy, 700115 Iași, Romania.ORCID 0000-0003-2640-8795
Ancuța LupuGrigore T. Popa University of Medicine and Pharmacy, 700115 Iași, Romania.ORCID 0000-0001-8147-3632
Alice GrudnickiGrigore T. Popa University of Medicine and Pharmacy, 700115 Iași, Romania.
Manuel Florin RoșuGrigore T. Popa University of Medicine and Pharmacy, 700115 Iași, Romania.
Roxana ȘerbanGrigore T. Popa University of Medicine and Pharmacy, 700115 Iași, Romania.
Andreea-Luciana AvasiloaieiGrigore T. Popa University of Medicine and Pharmacy, 700115 Iași, Romania.ORCID 0000-0002-5187-9938
Paula PopoviciGrigore T. Popa University of Medicine and Pharmacy, 700115 Iași, Romania.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Asthma prevalence in school-age children varies widely by geography, from below 5% in some regions to above 20% in others, averaging 10-12% across industrialized countries, but genetic factors account for less than 40% of disease liability. Gut microbiota is increasingly recognized as a critical intermediary between early-life dietary exposure and immunological trajectories that determine asthma susceptibility. Through the production of short-chain fatty acids (SCFAs), particularly butyrate, propionate, and acetate, commensal bacteria regulate dendritic cell function, promote T-regulatory (Treg) cell differentiation, and attenuate Th2-polarized airway inflammation via the gut-lung axis. Epidemiological cohorts including CHILD, WHEALS, and PASTURE associate early-life dysbiosis and reduced

Indexed as

AsthmaDietDysbiosisGastrointestinal MicrobiomeChildHumansInflammationairway inflammationbutyratedietary patternsdysbiosisgut–lung axisgut microbiotanutritionobesity-related asthmapaediatric asthmashort-chain fatty acids

Identifiers

PMID42588119
PMCPMC13467618

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.