Evidence map›Paper›PMID 42587732›Full record

ArticleCells2026

The Antidepressant Vortioxetine Potently Inhibits Cell Growth in Cultured Human Glioblastoma Cells Expressing 5-HT

Veronica Russo, Miriam Russo, Maria Antonietta Oliva, Marika Alborghetti, Sonia Castaldi, Luisa Di Menna, Giuseppe Battaglia, Ferdinando Nicoletti, Matteo Caridi, Antonietta Arcella

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cells, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Veronica RussoIRCCS Neuromed, Via Atinense, 86077 Pozzilli, Italy.ORCID 0009-0003-1705-2448
Miriam RussoIRCCS Neuromed, Via Atinense, 86077 Pozzilli, Italy.ORCID 0009-0000-0463-4914
Maria Antonietta OlivaIRCCS Neuromed, Via Atinense, 86077 Pozzilli, Italy.
Marika AlborghettiDepartment of Neuroscience, Mental Health and Sensory Organs, Sapienza University of Rome, 00189 Rome, Italy.
Sonia CastaldiIRCCS Neuromed, Via Atinense, 86077 Pozzilli, Italy.
Luisa Di MennaIRCCS Neuromed, Via Atinense, 86077 Pozzilli, Italy.ORCID 0000-0003-0840-8150
Giuseppe BattagliaIRCCS Neuromed, Via Atinense, 86077 Pozzilli, Italy.ORCID 0000-0001-7571-3417
Ferdinando NicolettiIRCCS Neuromed, Via Atinense, 86077 Pozzilli, Italy.
Matteo CaridiDepartment of Physiology and Pharmacology, Sapienza University, 00185 Rome, Italy.
Antonietta ArcellaIRCCS Neuromed, Via Atinense, 86077 Pozzilli, Italy.ORCID 0000-0002-0708-8282

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Antidepressive AgentsGlioblastomaReceptor, Serotonin, 5-HT1BVortioxetineCell Line, TumorCell ProliferationDuloxetine HydrochlorideFluoxetineHumansAntidepressive AgentsDuloxetine HydrochlorideFluoxetineReceptor, Serotonin, 5-HT1BVortioxetine5-HT1BduloxetinefluoxetineGBMVx

Identifiers

PMID42587732
PMCPMC13464444

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.