Evidence map›Paper›PMID 42587425›Full record

ArticleThe Gerontologist2026

Gender affirmation among transgender and gender-diverse people in middle age and late life: a scoping review.

Chenxi Yang, Yu-Te Huang, Yue Xu, Peter A Newman

Abstract readScoping Review
In one paragraph

Article in The Gerontologist, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Chenxi YangDepartment of Social Work and Social Administration, The University of Hong Kong, Hong Kong, Mainland China.
Yu-Te HuangDepartment of Social Work and Social Administration, The University of Hong Kong, Hong Kong, Mainland China.ORCID 0000-0002-6861-8144
Yue XuDepartment of Social Work and Social Administration, The University of Hong Kong, Hong Kong, Mainland China.ORCID 0000-0001-5239-7378
Peter A NewmanFactor-Inwentash Faculty of Social Work, University of Toronto, Toronto, Ontario, Canada.

Funding

General Research Fund, Research Grants Council 17615523Social Sciences and Humanities Research Council of Canada 895-2019-1020
6 · The paper itself

Abstract

BACKGROUND AND

objectivesAlthough gender affirmation is a social determinant of health for transgender and gender-diverse people, reviews have predominantly focused on the medical domain and on younger populations. We conducted a scoping review by mapping peer-reviewed studies on 4 domains of gender affirmation among transgender and gender-diverse people in middle age and late life. RESEARCH DESIGN AND

methodsUsing the Joanna Briggs Institute's scoping review methodology and PRISMA-ScR reporting guidelines, we conducted a literature search of the following databases: MEDLINE, Social Work Abstracts, CINAHL PLUS from EBSCOhost, APA PsycINFO, ASSIA, Sociological Abstracts from ProQuest, and SCOPUS. Of the 1,339 studies identified, 58 were included in this review. We used a hybrid thematic content analysis to synthesize the key findings.

resultsThe participants reported both gender-affirming and non-affirming experiences in (a) the psychological domain, which includes identity confusion, dysphoria, internalized stigma, and self-acceptance and identity realization in later life; (b) the social domain, which encapsulates decisions to conceal or disclose their gender identity, experiences of rejection or support, and community engagement and advocacy actions; (c) the medical domain, which concerns access to and experiences with gender-affirming care and non-affirming services in healthcare; and (d) the legal domain, which involves pursuing gender recognition, navigating legal documentation, and facing systemic barriers in end-of-life planning. DISCUSSION AND IMPLICATIONS: This review highlights the multi-dimensional needs associated with gender affirmation and the systemic barriers faced by transgender and gender-diverse adults in middle age and late life. It provides insight into gender-affirming experiences that can inform more age-friendly and gender-affirming care.

Indexed as

Transgender PersonsAgedFemaleGender IdentityGender-Nonconforming PersonsHumansMaleMiddle AgedSocial StigmaAgingGender affirmationOld ageReviewTransgender

Identifiers

PMID42587425
PMCPMC13541382

What OpenQuestion holds

Textmetadata
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.