Evidence map›Paper›PMID 42587237›Full record

ArticleNeurochemical research2026

IMD-1 Protects SH-SY5Y Cells Against H

Muazzez Derya-Andeden, Pinar Altin-Celik, Naciye Elif Tokguner, Ali Turan, Hamiyet Eciroglu-Sarban, Hamiyet Donmez-Altuntas

Abstract read
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Article in Neurochemical research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Muazzez Derya-AndedenDepartment of Medical Biology, Faculty of Medicine, Erciyes University, Kayseri, Türkiye. muazzezderya@erciyes.edu.tr.ORCID http://orcid.org/0000-0003-4390-5769
Pinar Altin-CelikDepartment of Medical Biology, Faculty of Medicine, Erciyes University, Kayseri, Türkiye.ORCID http://orcid.org/0000-0001-8429-009X
Naciye Elif TokgunerDepartment of Medical Biology, Faculty of Medicine, Erciyes University, Kayseri, Türkiye.ORCID http://orcid.org/0009-0002-4130-533X
Ali TuranDepartment of Bioengineering, Faculty of Life and Natural Sciences, Abdullah Gül University, Kayseri, Türkiye.ORCID http://orcid.org/0000-0002-5751-5473
Hamiyet Eciroglu-SarbanProgram of Medical Laboratory Techniques, Vocational School of Health Services, Alanya Alaaddin Keykubat University, Antalya, Türkiye.ORCID http://orcid.org/0000-0002-3555-3946
Hamiyet Donmez-AltuntasDepartment of Medical Biology, Faculty of Medicine, Erciyes University, Kayseri, Türkiye.ORCID http://orcid.org/0000-0001-6473-5813

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oxidative stress, mitochondrial dysfunction, inflammation-associated cellular responses, and apoptosis are closely associated with the pathogenesis of neurodegenerative disorders. Therefore, identifying small molecules capable of modulating these interconnected cellular processes is important for the development of potential neuroprotective strategies. The present study investigated the protective effects of the imidazole derivative (IMD)-1 against hydrogen peroxide (H

Indexed as

ApoptosisEnergy MetabolismHydrogen PeroxideImidazolesInflammation MediatorsMitochondriaNeuroprotective AgentsOxidative StressCell Line, TumorCell SurvivalHumansMembrane Potential, MitochondrialReactive Oxygen SpeciesHydrogen PeroxideImidazolesInflammation MediatorsNeuroprotective AgentsReactive Oxygen SpeciesApoptosisImidazole derivativeMitochondrial dysfunctionNeuroprotectionOxidative stressSH-SY5Y cells

Identifiers

PMID42587237

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.