Evidence map›Paper›PMID 42587043›Full record

ArticleSurgical endoscopy2026

Laparoscopic versus open sectionectomy and bisectionectomy for hepatocellular carcinoma: a propensity score-matched analysis of short- and long-term outcomes.

Thanh Tung Lai, Kosuke Matsui, Hisashi Kosaka, Hideyuki Matsushima, Hidekazu Yamamoto, Gozo Kiguchi, Takuya Ohigashi, Van Khanh Nguyen, Hoang Hai Duong, Kyoko Inoue and 3 more

Abstract read
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Article in Surgical endoscopy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Thanh Tung LaiDepartment of Hepatobiliary Surgery, Kansai Medical University, 2-5-1, Shin-Machi, Hirakata, Osaka, 573-1010, Japan.
Kosuke MatsuiDepartment of Hepatobiliary Surgery, Kansai Medical University, 2-5-1, Shin-Machi, Hirakata, Osaka, 573-1010, Japan.
Hisashi KosakaDepartment of Hepatobiliary Surgery, Kansai Medical University, 2-5-1, Shin-Machi, Hirakata, Osaka, 573-1010, Japan.
Hideyuki MatsushimaDepartment of Hepatobiliary Surgery, Kansai Medical University, 2-5-1, Shin-Machi, Hirakata, Osaka, 573-1010, Japan.
Hidekazu YamamotoDepartment of Hepatobiliary Surgery, Kansai Medical University, 2-5-1, Shin-Machi, Hirakata, Osaka, 573-1010, Japan.
Gozo KiguchiDepartment of Hepatobiliary Surgery, Kansai Medical University, 2-5-1, Shin-Machi, Hirakata, Osaka, 573-1010, Japan.
Takuya OhigashiDepartment of Hepatobiliary Surgery, Kansai Medical University, 2-5-1, Shin-Machi, Hirakata, Osaka, 573-1010, Japan.
Van Khanh NguyenDepartment of Hepatobiliary Surgery, Kansai Medical University, 2-5-1, Shin-Machi, Hirakata, Osaka, 573-1010, Japan.
Hoang Hai DuongDepartment of Hepatobiliary Surgery, Kansai Medical University, 2-5-1, Shin-Machi, Hirakata, Osaka, 573-1010, Japan.
Kyoko InoueDepartment of Hepatobiliary Surgery, Kansai Medical University, 2-5-1, Shin-Machi, Hirakata, Osaka, 573-1010, Japan.
Moriyasu TakadaDepartment of Hepatobiliary Surgery, Kansai Medical University, 2-5-1, Shin-Machi, Hirakata, Osaka, 573-1010, Japan.
Kengo YoshiiDepartment of Mathematics and Statistics in Medical Sciences, Kyoto Prefectural University of Medicine, Kyoto, Japan.
Masaki KaiboriDepartment of Hepatobiliary Surgery, Kansai Medical University, 2-5-1, Shin-Machi, Hirakata, Osaka, 573-1010, Japan. kaibori.mas@kmu.ac.jp.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis study aimed to compare short- and long-term outcomes of laparoscopic hepatectomy (LH) versus open hepatectomy (OH) in patients with HCC who underwent sectionectomies or bisectionectomies.

methodsFrom 2018 to 2023, HCC patients who underwent a sectionectomy or bisectionectomy were retrospectively analyzed. Propensity score matching (PSM) was used to assess the association of operative approaches with short- and long-term outcomes.

resultsAmong 112 patients with HCC, 49 (43.8%) and 63 (56.2%) underwent LH and OH, respectively. Compared with OH, LH was respectively associated with lower blood loss (844 vs. 307 mL, p < 0.001), shorter hospital stay (20 vs. 15 days, p = 0.010), lower rates of severe postoperative complications (33% vs. 14%, p = 0.032) and overall infections (40% vs. 20%, p = 0.029), and organ/space surgical site infections (30% vs. 10%, p = 0.011). After PSM, LH remained superior regarding blood loss, hospital stay, severe postoperative complications, overall infections, and organ/space SSIs (323 mL, 15 days, 17, 19, and 11% vs. 762 mL, 22 days, 39, 47, and 36%, respectively). The patients undergoing LH had lower C-reactive protein (CRP) levels (p = 0.006), longer prothrombin time (p = 0.012), and higher cholinesterase levels (p = 0.046) than the patients undergoing OH throughout the postoperative period. The differences between the 5-year OS (57.1% vs. 46.7%, p = 0.685) and RFS (34.9% vs. 26.8%, p = 0.475) rates of the respective LH and OH patients were not significant.

conclusionsLaparoscopic sectionectomies and bisectionectomies for patients with HCC are feasible and safe, with better short-term outcomes than open sectionectomies and bisectionectomies, and provide similar long-term outcomes.

Indexed as

BisectionectomyLaparoscopic hepatectomyMinimally invasive surgeryOutcomesSectionectomy

Identifiers

PMID42587043

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.