Evidence map›Paper›PMID 42587029›Full record

ArticleJournal of perinatology : official journal of the California Perinatal Association2026

Early autism risk factors: a cohort study of children born very preterm at 5-years.

Meg Stone-Heaberlin, Allison D Blackburn, Leanne Tamm, Armin Allahverdy, Beth Kline-Fath, Nehal A Parikh

Abstract read
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In one paragraph

Article in Journal of perinatology : official journal of the California Perinatal Association, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Meg Stone-Heaberlin *Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.ORCID http://orcid.org/0000-0002-6373-7697
Allison D Blackburn *Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.ORCID http://orcid.org/0000-0003-1032-9494
Leanne TammDepartment of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA. leanne.tamm@cchmc.org.ORCID http://orcid.org/0000-0001-6066-1669
Armin AllahverdyDepartment of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.ORCID http://orcid.org/0000-0002-1507-1819
Beth Kline-FathDepartment of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.ORCID http://orcid.org/0000-0003-3872-9027
Nehal A ParikhDepartment of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.ORCID http://orcid.org/0000-0002-1375-1247

Funding

A New Model to Identify Preterm Neonates at High-Risk for Cognitive Impairments and School ReadinessR01NS094200 · NINDS · CINCINNATI CHILDRENS HOSP MED CTR · PI NEHAL A. PARIKH · 2016 to 2026
$6.7M
Early Prediction of Cerebral Palsy in Premature Infants using Advanced MRI BiomarkersR01NS096037 · NINDS · CINCINNATI CHILDRENS HOSP MED CTR · PI PARIKH, NEHAL A. · 2016 to 2020
$2.2M
NINDS NIH HHS R01 NS094200NINDS NIH HHS R01 NS096037U.S. Department of Health & Human Services | NIH | National Institute of Neurological Disorders and Stroke (NINDS) R01-NS094200U.S. Department of Health & Human Services | NIH | National Institute of Neurological Disorders and Stroke (NINDS) R01-NS096037
6 · The paper itself

Abstract

objectiveExplore the association of prenatal, perinatal, and postnatal risk factors with autism risk at 5-years corrected age in very preterm (VPT) children. STUDY

designData from a longitudinal cohort study of 315 VPT and 172 term-born children at a US-based academic medical center were analyzed, exploring antecedents of autism risk using elastic net regression.

resultsMore children born VPT (8.9%) had a Social Communication Questionnaire score associated with autism (i.e., SCQ ≥ 15) than term-born controls (2.9%; p = 0.012). For VPT children, cerebellar abnormalities at term-equivalent age (OR = 1.339, 95% CI = 1.010-1.778) and moderate-severe histologic chorioamnionitis (OR = 4.148, CI = 1.294-13.368) were significantly associated with autism risk, in addition to male sex and social risk. VPT children with SCQ ≥ 15 had poorer adaptive, behavioral, cognitive, and executive functioning (all ps < 0.001).

conclusionEarly screening for children with these risk factors can facilitate early intervention for those at most risk for poorer neurodevelopmental outcomes.

Identifiers

PMID42587029
PMCPMC13531389

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.