Evidence map›Paper›PMID 42586993›Full record

ArticleScientific reports2026

Synthesis of novel 11H-indeno[1,2-b]quinoxaline derivatives and their in vitro and in silico insights into anticancer activities.

Fatma A El-Samahy, Ghada A Eldeken, Ehab M Zayed, Fayez H Osman, Khaled Mahmoud, Galal E H Elgemeie

Abstract read
In one paragraph

Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Chemistry and Biological Activity of 11Molecules (Basel, Switzerland) · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Fatma A El-SamahyDepartment of Green Chemistry, Chemical Industries Research Institute, National Research Centre, 33 El‑Buhouth St, Dokki, Giza, 12622, PO, Egypt. samahyf@hotmail.com.
Ghada A EldekenDepartment of Green Chemistry, Chemical Industries Research Institute, National Research Centre, 33 El‑Buhouth St, Dokki, Giza, 12622, PO, Egypt.
Ehab M ZayedDepartment of Green Chemistry, Chemical Industries Research Institute, National Research Centre, 33 El‑Buhouth St, Dokki, Giza, 12622, PO, Egypt.
Fayez H OsmanDepartment of Green Chemistry, Chemical Industries Research Institute, National Research Centre, 33 El‑Buhouth St, Dokki, Giza, 12622, PO, Egypt.
Khaled MahmoudPharmacognosy Department, National Research Centre, 33 El‑Buhouth St, Dokki, Giza, 12622, PO, Egypt.
Galal E H ElgemeieChemistry Department, Faculty of Science, Capital University, Helwan, Cairo, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the present work a novel series of 11H-indeno[1,2-b]quinoxaline derivatives were rationally designed and synthesised, with the aim of exploring their potential anticancer properties.The novel compounds were studied by IR,

Indexed as

Antineoplastic AgentsQuinoxalinesCell Line, TumorComputer SimulationDrug Screening Assays, AntitumorHCT116 CellsHumansMCF-7 CellsMolecular Docking SimulationStructure-Activity RelationshipAntineoplastic AgentsQuinoxalines11-Hydrazineylidene-11H-indeno[1,2-b]quinoxalineAntitumor activityMolecular dockingPhosphonatesSwissADME studies

Identifiers

PMID42586993
PMCPMC13469509

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.