Evidence map›Paper›PMID 42586735›Full record

ArticleBMJ open2026

COVID-19 vaccination among people affected by sexually transmitted and bloodborne infections, methamphetamine use and their intersection in Manitoba, Canada: a retrospective matched cohort analysis using population-based administrative healthcare data (2020-2022).

Souradet Y Shaw, Alyson Mahar, Kim Bailey, Michael Payne, Jason Kindrachuk, Christine Kelly, Kevin J Friesen, Charles N Bernstein, Joss N Reimer, Marissa L Becker and 3 more

Abstract read
In one paragraph

Article in BMJ open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Souradet Y ShawCollege of Community and Global Health, University of Manitoba, Winnipeg, Manitoba, Canada souradet.shaw@umanitoba.ca.ORCID http://orcid.org/0000-0002-0982-1302
Alyson MaharSchool of Nursing, Queen's University, Kingston, Ontario, Canada.
Kim BaileyNine Circles Community Health Centre, Winnipeg, Manitoba, Canada.
Michael PayneNine Circles Community Health Centre, Winnipeg, Manitoba, Canada.
Jason KindrachukDepartment of Medical Microbiology and Infectious Diseases, University of Manitoba, Winnipeg, Manitoba, Canada.ORCID http://orcid.org/0000-0002-3305-7084
Christine KellyCollege of Community and Global Health, University of Manitoba, Winnipeg, Manitoba, Canada.
Kevin J FriesenManitoba Centre for Health Policy, University of Manitoba, Winnipeg, Manitoba, Canada.
Charles N BernsteinDepartment of Internal Medicine, University of Manitoba, Winnipeg, Manitoba, Canada.ORCID http://orcid.org/0000-0001-8041-3574
Joss N ReimerPublic Health Agency of Canada, Ottawa, Ontario, Canada.
Marissa L BeckerCollege of Community and Global Health, University of Manitoba, Winnipeg, Manitoba, Canada.ORCID http://orcid.org/0000-0002-9235-0547
Leigh Michelle McClartyCollege of Community and Global Health, University of Manitoba, Winnipeg, Manitoba, Canada.ORCID http://orcid.org/0000-0003-0183-2768
Derek SteinDepartment of Medical Microbiology and Infectious Diseases, University of Manitoba, Winnipeg, Manitoba, Canada.
Nathan C NickelCollege of Community and Global Health, University of Manitoba, Winnipeg, Manitoba, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo examine COVID-19 vaccine uptake among people diagnosed with sexually transmitted and bloodborne infections (STBBIs), people with healthcare-documented methamphetamine use and those experiencing both exposures in Manitoba, Canada.

designPopulation-based retrospective matched cohort study using linked administrative healthcare, laboratory and vaccination data.

settingManitoba, Canada, from 1 March 2020 to 31 March 2022.

participantsManitoba residents aged ≥16 years with laboratory-confirmed chlamydia or gonorrhoea, syphilis or HIV and/or healthcare-documented methamphetamine use during the 4 years before 1 March 2020 were classified into eight mutually exclusive exposure cohorts. Individuals were matched with comparators without the corresponding exposure based on age, sex, geographical region and area-level income quintile. PRIMARY OUTCOME MEASURE: Receipt of ≥2 COVID-19 vaccine doses. Poisson regression models incorporating person-time were used to estimate adjusted rate ratios (aRRs) and 95% CIs.

resultsCompared with matched comparators, vaccine uptake was lower in the Syphilis Only (aRR 0.83, 95% CI 0.80 to 0.86), Syphilis Plus (aRR 0.77, 95% CI 0.74 to 0.79), Chlamydia/Gonorrhoea Only (aRR 0.91, 95% CI 0.90 to 0.92), Chlamydia/Gonorrhoea Plus (aRR 0.74, 95% CI 0.72 to 0.77), Methamphetamine Only (aRR 0.71, 95% CI 0.68 to 0.73) and Methamphetamine plus STBBI cohorts (aRR 0.64, 95% CI 0.62 to 0.67). Uptake in the HIV Only cohort was similar to that among matched comparators (aRR 0.97, 95% CI 0.93 to 1.00). Lower uptake was concentrated among individuals living in lower-income areas.

conclusionsCOVID-19 vaccine uptake was lower among several populations affected by STBBIs, methamphetamine use or both, with the greatest disparity among people experiencing intersecting STBBI and methamphetamine-related exposures. Integrating vaccination with HIV, STBBI, harm-reduction and addiction services may improve vaccine equity during future public health emergencies.

Indexed as

Amphetamine-Related DisordersCOVID-19COVID-19 VaccinesMethamphetamineSexually Transmitted DiseasesVaccinationAdolescentAdultFemaleHumansMaleManitobaMiddle AgedRetrospective StudiesSARS-CoV-2Young AdultCOVID-19 VaccinesMethamphetamineCOVID-19EPIDEMIOLOGYHIV & AIDSSyphilisVaccination

Identifiers

PMID42586735
PMCPMC13475451

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.