Evidence map›Paper›PMID 42585884›Full record

ReviewJournal of optometry2026

Diagnostic accuracy of objective measures for ocular malingering: A systematic review.

Emmanuel Ekow Ampiah, Patrick Evans Agyiri, Gideon Owusu, Daniel Miezah, Richmond Panyin, Clara Efua Ayandoh

Abstract readReview
In one paragraph

Review in Journal of optometry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Emmanuel Ekow AmpiahDepartment of Vision Science, School of Optometry and Vision Science, University of Cape Coast, Cape Coast, Ghana. Electronic address: emmanuel.ampiah@ucc.edu.gh.
Patrick Evans AgyiriDepartment of Clinical Optometry, School of Optometry and Vision Science, University of Cape Coast, Ghana.
Gideon OwusuDepartment of Clinical Optometry, School of Optometry and Vision Science, University of Cape Coast, Ghana.
Daniel MiezahDepartment of Education and Psychology, Faculty of Educational Foundation, University of Cape Coast, Ghana.
Richmond PanyinDepartment of Education and Psychology, Faculty of Educational Foundation, University of Cape Coast, Ghana.
Clara Efua AyandohDepartment of Clinical Optometry, School of Optometry and Vision Science, University of Cape Coast, Ghana.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate the diagnostic accuracy of objective tests including Visual Evoked Potentials (VEP), pupillometry, and eye-tracking technologies in detecting ocular malingering among individuals suspected of fabricating visual impairments for secondary gain.

methodsFollowing PRISMA guidelines, PubMed, Web of Science, Scopus, EMBASE, and Cochrane Library were searched until June 2025. Studies evaluating objective diagnostic methods for detecting ocular malingering that reported diagnostic accuracy metrics were included. Two reviewers performed data extraction and quality assessment using QUADAS-2.

resultsTen studies from 1993 to 2017 with 20 to 222 subjects were included. Approximately half of the studies employed experimentally simulated malingering paradigms, while the remainder involved clinically suspected cases. VEP was the most frequently evaluated modality and showed high sensitivity across studies, although specificity varied. Pattern-reversal VEPs showed effectiveness in adults and military conscripts, while step VEPs demonstrated 100% specificity in paediatric cases. Pupillometry and specialised colour vision tests achieved 80-94% sensitivity and specificity rates. Most studies showed low bias risk in index test and reference standard domains. These findings suggest potential utility of objective tools as adjuncts in clinical and medico-legal settings.

conclusionObjective diagnostic measures demonstrate promising utility as adjunctive tools for detecting ocular malingering and may support clinical decision making by providing reproducible assessments that bypass voluntary patient control. However, heterogeneity in study designs limits generalisability. Future research should standardise protocols and validate findings across diverse populations.

Indexed as

Diagnostic accuracyObjective measuresOcular malingeringSystematic reviewVisual evoked potentials

Identifiers

PMID42585884
PMCPMC13486990

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.