Evidence map›Paper›PMID 42585559›Full record

SynthesisAge and ageing2026

Validation of the World Falls Guidelines risk stratification algorithm. A systematic review.

Frederico Pieruccini-Faria, Surim Son, Kim Delbaere, Nathalie van der Velde, Stephen R Lord, Finbarr C Martin, Jesper Ryg, Maw Pin Tan, Teresa Liu-Ambrose, Diana Amaris and 3 more

Abstract readSystematic ReviewValidation Study
In one paragraph

Synthesis in Age and ageing, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Frederico Pieruccini-FariaDepartment of Medicine, Division of Geriatric Medicine, Schulich School of Medicine & Dentistry, Western University, 1151 Richmond Street, London, Ontario N6C 3K7, Canada.ORCID 0000-0002-7659-4285
Surim SonDepartment of Epidemiology and Biostatistics, Schulich School of Medicine & Dentistry, Western University, 1151 Richmond Street, London, Ontario N6C 3K7, Canada.
Kim DelbaereSchool of Health Sciences, University of New South Wales, Health Translation Hub, Randwick, New South Wales 2031, Australia.ORCID 0000-0002-5655-0234
Nathalie van der VeldeAmsterdam UMC-Locatie AMC-Internal Medicine, Section of Geriatric Medicine, Amsterdam Public Health, Meibergdreef 9, Amsterdam, North Holland 1105 AZ, Netherlands.ORCID 0000-0002-6477-6209
Stephen R LordNeuroscience Research Australia, UNSW, Sydney, New South Wales, Australia.ORCID 0000-0002-7111-8802
Finbarr C MartinPopulation Health Sciences, King's College London Faculty of Life Sciences & Medicine, Addison House, Guy's Campus Great Maze Road, London SE1 9RT, UK.ORCID 0000-0002-6911-3498
Jesper RygDepartment of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.ORCID 0000-0002-8641-3062
Maw Pin TanDepartment of Medicine, Faculty of Medicine Universiti Malaya (University of Malaya) Kuala Lumpur, Malaysia.ORCID 0000-0002-3400-8540
Teresa Liu-AmbroseFaculty of Medicine, The University of British Columbia, Vancouver, British Columbia, Canada.ORCID 0000-0002-8297-5308
Diana AmarisMedicine, Lawson Health Research Institute, London, Ontario, Canada.
Cameron HicksNeuroscience Research Australia, 139 Barker St, Randwick, New South Wales 2031, Australia.ORCID 0000-0001-6537-0158
Tahir MasudHealthcare for Older People, Nottingham University Hospitals NHS Trust, Queens Medical Centre Campus, Nottingham NG7 2UH, UK.ORCID 0000-0003-1061-2898
Manuel Montero-OdassoDepartment of Medicine, Division of Geriatric Medicine, Schulich School of Medicine & Dentistry, Western University, 1151 Richmond Street, London, Ontario N6C 3K7, Canada.ORCID 0000-0002-5796-2361

Funding

CIHR |nstitute of Aging PJT153100
6 · The paper itself

Abstract

backgroundFalls are a major cause of morbidity and mortality in older adults. The World Falls Guidelines (WFG) propose a risk stratification algorithm using fall history, three key questions (3KQ), mobility tests and clinical criteria, but it has yet to be systematically evaluated.

objectiveTo assess whether the WFG algorithm, in original or modified form, effectively stratifies community-dwelling older adults into low, intermediate or high risk of future falls; whether it has been prospectively validated; and whether it has been adequately operationalised.

methodsWe conducted a systematic review (PROSPERO CRD420251151506) by searching MEDLINE, Embase and Google Scholar. Two reviewers independently screened studies and extracted data on cohort characteristics, algorithm adaptations, baseline risk distribution and prospective falls outcomes over ≥6 months. Given the heterogeneity of the studies included, quantitative meta-analysis was not conducted.

resultsEight cohort studies (n = 25 027; mean age range 61-82 years) met the inclusion criteria. No study implemented the WFG algorithm as published; two used minor modifications and six had major adaptations due to dataset limitations. Common modifications included rephrasing the 3KQ, replacing 'subjective unsteadiness' question with objective measures, applying mobility test universally, adjusting mobility tests thresholds and omitting fall severity definition components. Across studies, 7.9%-82.6% of participants were classified as low risk, 0.4%-18.3% as intermediate risk and 10.5%-88.7% as high risk. High-risk classification showed modest sensitivity (26.5%-52.3%) and moderate-to-high specificity (34.2%-88.9%) for future falls (1-2 years), with an overall accuracy of 61.2%-74.2%. High-risk groups consistently had a two- to three-fold higher incidence of falls than low-risk groups, while intermediate-risk groups only showed a slightly elevated risk. Use of 3KQ alongside fall history and universal mobility testing improved discrimination and increased the proportion in the intermediate-risk category.

conclusionThe operationalised versions of the WFG algorithm identify older adults at high falls risk with high specificity but limited sensitivity. Proposed pragmatic modifications improve stratification accuracy for intermediate risk group but require prospective validation.

Indexed as

Accidental FallsAlgorithmsGeriatric AssessmentPractice Guidelines as TopicAgedAged, 80 and overAge FactorsFemaleHumansMaleMiddle AgedPredictive Value of TestsReproducibility of ResultsRisk AssessmentRisk Factorsfallsfalls algorithmfalls in older adultsguidelinesolder peoplesystematic review

Identifiers

PMID42585559
PMCPMC13464692

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.