Evidence map›Paper›PMID 42585422›Full record

Observational studyRevista da Associacao Medica Brasileira (1992)2026

Clinical profile of acute myocardial infarction: the Registry of Acute Medical Emergencies registry.

Pedro Gabriel Melo de Barros E Silva, Alexandre Matos Soeiro, Rodrigo Balada, Lucas Macedo, Milena Del Valle de Lacerda, Luan Vitor Aguiar Correia, Maria Carolina Ximenes, Karen Teixeira Dias, Sabrina Carvalho Moura, Sofia Gabriela Gregolini Catellani and 1 more

Erratum issued Registry-linked trialAbstract readObservational StudyMulticenter Study
In one paragraph

Observational study in Revista da Associacao Medica Brasileira (1992), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to trial NCT02753023 (Registry Of Acute meDical Emergencies in Brazil - ROAD-Brazil), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02753023 unknown statusnot on this map

Registry Of Acute meDical Emergencies in Brazil - ROAD-Brazil

Typeobservational_patient_registrySponsorUniversity of Sao Paulo General HospitalRan2015 to 2020Enrolled1,650ConditionsAcute Coronary Syndromes, Heart Failure, Pulmonary Edema, Aortic Aneurysm, Familial Thoracic 1Armsno intervention
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

Pedro Gabriel Melo de Barros E SilvaHospital Samaritano Paulista - São Paulo (SP), Brazil.ORCID http://orcid.org/0000-0003-1940-4470
Alexandre Matos SoeiroUniversidade de São Paulo, Heart Institute - São Paulo (SP), Brazil.ORCID http://orcid.org/0000-0002-3777-1947
Rodrigo BaladaCentro Universitário São Camilo - São Paulo (SP), Brazil.ORCID http://orcid.org/0009-0008-8836-2060
Lucas MacedoCentro Universitário São Camilo - São Paulo (SP), Brazil.ORCID http://orcid.org/0000-0003-4463-3291
Milena Del Valle de LacerdaCentro Universitário São Camilo - São Paulo (SP), Brazil.ORCID http://orcid.org/0009-0000-5309-2226
Luan Vitor Aguiar CorreiaCentro Universitário São Camilo - São Paulo (SP), Brazil.ORCID http://orcid.org/0009-0005-2688-7978
Maria Carolina XimenesCentro Universitário São Camilo - São Paulo (SP), Brazil.ORCID http://orcid.org/0009-0004-9796-6430
Karen Teixeira DiasCentro Universitário São Camilo - São Paulo (SP), Brazil.ORCID http://orcid.org/0009-0004-6549-8142
Sabrina Carvalho MouraCentro Universitário São Camilo - São Paulo (SP), Brazil.ORCID http://orcid.org/0009-0007-8295-4957
Sofia Gabriela Gregolini CatellaniCentro Universitário São Camilo - São Paulo (SP), Brazil.ORCID http://orcid.org/0009-0007-1758-7871
Renato Deslacio LopesBrazilian Clinical Research Institute - São Paulo (SP), Brazil.ORCID http://orcid.org/0000-0003-2999-4961

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionAround 30% of patients with acute myocardial infarction do not report chest pain, but data on symptom patterns according to the type of myocardial infarction and attending physician specialty are scarce.

objectiveThe aim of this study was to identify common clinical presentations of acute myocardial infarction in a Brazilian registry, stratified by infarction type and physician specialty.

methodsObservational analysis of two datasets: (1) retrospective cohort of 2,783 acute myocardial infarction patients from 15 hospitals (2014-2018) initially evaluated by emergency physicians; (2) prospective registry of 718 acute myocardial infarction patients (2018-2020) assessed in the acute phase by cardiologists via telemedicine. Cases were classified as ST-segment Elevation Myocardial Infarction or Non-ST-segment Elevation Myocardial Infarction. Symptoms were categorized as typical/atypical chest pain, epigastric pain, or absence of both; additional symptoms were recorded. Categorical variables were compared using chi-square tests (p<0.05).

resultsTypical chest pain occurred in 60.3% of patients, more frequent in ST-segment Elevation Myocardial Infarction than Non-ST-segment Elevation Myocardial Infarction (66.5 vs. 56.5%; p<0.01). Absence of chest/epigastric pain was more common in Non-ST-segment Elevation Myocardial Infarction (6.1%) than ST-segment Elevation Myocardial Infarction (2.7%) (p<0.01). Cardiologist assessment identified more acute myocardial infarction cases without chest/epigastric pain than emergency physician assessment (11.0 vs. 3.2%; p<0.01). ST-segment Elevation Myocardial Infarction patients without chest/epigastric pain had the highest mortality (29.4%) in the emergency physician cohort.

conclusionIn this registry, absence of chest or epigastric pain was less frequent than previously reported but associated with high mortality. Telemedicine evaluation by cardiologists identified a greater proportion of pain-free acute myocardial infarction presentations. CLINICAL TRIAL REGISTRATION NUMBER: ClinicalTrials.gov NCT02753023.

Indexed as

Myocardial InfarctionAgedBrazilChest PainEmergency Medical ServicesFemaleHumansMaleMiddle AgedNon-ST Elevated Myocardial InfarctionProspective StudiesRegistriesRetrospective StudiesST Elevation Myocardial Infarction

Identifiers

PMID42585422
PMCPMC13459720

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.