In one paragraphArticle in Science advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
22 authors.
Peng ZhangDepartment of Integration of Chinese and Western Medicine, School of Basic Medical Sciences, Department of Interventional Radiology and Vascular Surgery, Third Hospital, Peking University, Beijing, China.ORCID 0000-0001-7042-8000 Jinman ZhuangDepartment of Integration of Chinese and Western Medicine, School of Basic Medical Sciences, Department of Interventional Radiology and Vascular Surgery, Third Hospital, Peking University, Beijing, China.ORCID 0009-0004-7367-808X Xiangrui ZhuDepartment of Integration of Chinese and Western Medicine, School of Basic Medical Sciences, Department of Interventional Radiology and Vascular Surgery, Third Hospital, Peking University, Beijing, China.ORCID 0009-0001-2281-3825 Hongbiao LiangDepartment of Integration of Chinese and Western Medicine, School of Basic Medical Sciences, Department of Interventional Radiology and Vascular Surgery, Third Hospital, Peking University, Beijing, China.ORCID 0009-0002-6271-9371 Guizimeng HuDepartment of Integration of Chinese and Western Medicine, School of Basic Medical Sciences, Department of Interventional Radiology and Vascular Surgery, Third Hospital, Peking University, Beijing, China.ORCID 0009-0001-5508-6513 Peiyi LiDepartment of Integration of Chinese and Western Medicine, School of Basic Medical Sciences, Department of Interventional Radiology and Vascular Surgery, Third Hospital, Peking University, Beijing, China.ORCID 0009-0005-5217-8139 Yuwei SongDepartment of Integration of Chinese and Western Medicine, School of Basic Medical Sciences, Department of Interventional Radiology and Vascular Surgery, Third Hospital, Peking University, Beijing, China.ORCID 0000-0002-4956-227X Qijia LiuDepartment of Integration of Chinese and Western Medicine, School of Basic Medical Sciences, Department of Interventional Radiology and Vascular Surgery, Third Hospital, Peking University, Beijing, China.ORCID 0000-0003-3867-3318 Guangxin YangDepartment of Integration of Chinese and Western Medicine, School of Basic Medical Sciences, Department of Interventional Radiology and Vascular Surgery, Third Hospital, Peking University, Beijing, China.ORCID 0000-0002-9540-8089 Tianqi ChenDepartment of Integration of Chinese and Western Medicine, School of Basic Medical Sciences, Department of Interventional Radiology and Vascular Surgery, Third Hospital, Peking University, Beijing, China.ORCID 0000-0002-8762-9682 Xinmei HuoDepartment of Integration of Chinese and Western Medicine, School of Basic Medical Sciences, Department of Interventional Radiology and Vascular Surgery, Third Hospital, Peking University, Beijing, China.ORCID 0009-0000-8149-8151 Kai SunTasly Microcirculation Research Center, Peking University Health Science Center, Beijing, China.ORCID 0009-0007-3103-8975 Li YanTasly Microcirculation Research Center, Peking University Health Science Center, Beijing, China.ORCID 0009-0006-1299-8105 Chun-Shui PanTasly Microcirculation Research Center, Peking University Health Science Center, Beijing, China.ORCID 0009-0005-7587-0048 Jing-Yan HanDepartment of Integration of Chinese and Western Medicine, School of Basic Medical Sciences, Department of Interventional Radiology and Vascular Surgery, Third Hospital, Peking University, Beijing, China.ORCID 0000-0002-2286-8076 Tianrun LiDepartment of Integration of Chinese and Western Medicine, School of Basic Medical Sciences, Department of Interventional Radiology and Vascular Surgery, Third Hospital, Peking University, Beijing, China.ORCID 0000-0002-1947-640X Jian-Hao ChenInternational Center for Quantum Materials, School of Physics, Peking University, Beijing, China.ORCID 0000-0002-9485-1759 Juan FengDepartment of Integration of Chinese and Western Medicine, School of Basic Medical Sciences, Department of Interventional Radiology and Vascular Surgery, Third Hospital, Peking University, Beijing, China.ORCID 0000-0003-0174-4784 Funding
No grant is acknowledged in the PubMed record.
6 · The paper itselfAbstract
Therapeutic angiogenesis based on gene therapies is a potential peripheral artery disease (PAD) treatment yet needs a more stable, efficient, and high-affinity delivery vector and an optimized delivery strategy. Here, we engineered three-dimensional graphene nanoparticles modified with folic acid and polyethyleneimine for macrophage-specific delivery of interleukin-4 plasmids (pIL-4), forming GNPs-pIL-4 for local intramuscular injection. GNPs-pIL-4 had uniform size, positive surface charge, and strong nucleic acid loading capacity (
Indexed as
AngiogenesisIschemiaMacrophagesNeovascularization, PhysiologicOncostatin MAnimalsCell PolarityGenetic TherapyHumansMacrophage ActivationMiceNanoparticlesPlasmidsOncostatin M
Identifiers
PMID42585315
PMCPMC13464477
What OpenQuestion holds
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