Evidence map›Paper›PMID 42585245›Full record

Observational studyClinical transplantation2026

Healthcare-Related Sociocultural Factors, Racial Disparities, and Kidney Transplant Outcomes in the Kidney Transplant Fast Track Program.

Miriam Vélez-Bermúdez, Yuridia Leyva, Chethan Puttarajappa, Arjun Kalaria, Yiliang Zhu, Yue-Harn Ng, Mark L Unruh, L Ebony Boulware, Amit Tevar, Mary Amanda Dew and 1 more

Registry-linked trialAbstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in Clinical transplantation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02342119 (Increasing Equity in Transplant Evaluation and Living Donor Kidney Transplantation), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02342119 nacompletednot on this map

Increasing Equity in Transplant Evaluation and Living Donor Kidney Transplantation

TypeinterventionalSponsorUniversity of PittsburghRan2015 to 2020Enrolled1,315ConditionsEnd-stage Kidney DiseaseArmsTalking About Living Kidney Donation, Kidney Transplant Fast Track
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Observational
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

Miriam Vélez-BermúdezCenter For Healthcare Evaluation in Kidney Disease (CHEK-D), School of Medicine, University of New Mexico, Albuquerque, New Mexico, USA.
Yuridia LeyvaCenter For Healthcare Evaluation in Kidney Disease (CHEK-D), School of Medicine, University of New Mexico, Albuquerque, New Mexico, USA.
Chethan PuttarajappaDepartment of Medicine, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Arjun KalariaFlorida Kidney Physicians, Tampa, Florida, USA.
Yiliang ZhuDepartment of Internal Medicine, School of Medicine, University of New Mexico, Albuquerque, New Mexico, USA.
Yue-Harn NgDepartment of Medicine, School of Medicine, University of Washington, Seattle, Washington, USA.
Mark L UnruhDepartment of Internal Medicine, School of Medicine, University of New Mexico, Albuquerque, New Mexico, USA.
L Ebony BoulwareSchool of Medicine, Wake Forest University, Charlotte, North Carolina, USA.
Amit TevarThomas E. Starzl Transplantation Institute, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.
Mary Amanda DewDepartment of Psychiatry, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Larissa MyaskovskyCenter For Healthcare Evaluation in Kidney Disease (CHEK-D), School of Medicine, University of New Mexico, Albuquerque, New Mexico, USA.

Funding

University of Pittsburgh Clinical and Translational Science InstituteUL1TR001857 · NCATS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI REIS, STEVEN E · 2016 to 2025
$129.3M
MINORITY INSTITUTIONAL RESEARCH TRAINING PROGRAM (T32)T32HL007736 · NHLBI · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI RESTA, THOMAS C · 1993 to 2025
$6.5M
Increasing Equity in Transplant Evaluation and Living Donor Kidney TransplantationR01DK101715 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI DEW, MARY AMANDA · 2014 to 2018
$2.7M
Dialysis Clinics C-3924NCATS NIH HHS UL1 TR001857NCATS NIH HHS UL1TR001857NHLBI NIH HHS T32 HL007736NHLBI NIH HHS T32HL007736NIDDK NIH HHS R01 DK101715NIDDK NIH HHS R01DK101715
6 · The paper itself

Abstract

backgroundIn the United States, streamlining the kidney transplantation (KT) evaluation process may reduce disparities and barriers to KT access. Prior work showed that the Kidney Transplant Fast Track (KTFT) program shortened this process and reduced racial disparities in waitlisting and overall KT. In the present study, we examined whether race/ethnicity and sociocultural factors (e.g., medical mistrust, healthcare-related discrimination/racism) remained independently associated with time to active waitlisting and KT receipt (overall, living [LDKT] and deceased donor KT [DDKT]) and whether sociocultural factors attenuated racial/ethnic differences in these outcomes.

methodsIn this secondary analysis, data came from the KTFT study, a prospective KT candidate cohort. Participants were recruited before KT evaluation start (05/2015-06/2018), coinciding with baseline measure collection, then followed via medical record through 08/2022. We used hierarchically-adjusted Fine-Gray proportional hazards models in this exploratory analysis.

resultsAmong 1108 KT candidates (243 Black, 783 White, 82 Other), medical mistrust was associated with lower cumulative incidence of waitlisting, but no other sociocultural factors were associated with outcomes. Racial and ethnic differences emerged for KT type: Black participants had a greater cumulative incidence of DDKT, and participants categorized as other race/ethnicity had a lower cumulative incidence of LDKT, relative to White participants.

conclusionsAlthough KTFT reduced racial/ethnic disparities in waitlisting and overall KT receipt, we identified racial/ethnic differences in LDKT and DDKT. Medical mistrust was a significant barrier to waitlisting. Findings suggest that even when the KT evaluation process is streamlined, sociocultural factors and race/ethnicity may remain associated with KT outcomes.

trial registrationClinicalTrials.gov identifier: NCT02342119.

Indexed as

EthnicityHealthcare DisparitiesKidney Failure, ChronicKidney TransplantationWaiting ListsAdultBlack or African AmericanFemaleFollow-Up StudiesGraft SurvivalHumansMaleMiddle AgedPrognosisProspective StudiesRandomized Controlled Trials as Topickidney transplantationkidney transplant outcomesracial and ethnic disparitiessociocultural factorstransplant evaluation

Identifiers

PMID42585245
PMCPMC13465735

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.