Evidence map›Paper›PMID 42584973›Full record

Observational studyJournal of obesity2026

Preoperative Cer(d18:1/24:0) Shows Promise as a Candidate Predictor of Plasma Lipid Phenotypes Following Roux-en-Y Gastric Bypass in Women: An Exploratory Analysis of the SURMetaGIT Study.

Gabriela de O Lemos, Raquel S M Torrinhas, Jéssica M Volejnik Pino, Philip C Calder, Steven B Heymsfield, Natasha M Machado, Dan L Waitzberg

Abstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in Journal of obesity, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Gabriela de O LemosDepartamento de Gastroenterologia, Universidade de São Paulo, São Paulo, São Paulo, Brazil, usp.br.ORCID https://orcid.org/0000-0003-0943-1387
Raquel S M TorrinhasDepartamento de Gastroenterologia, Universidade de São Paulo, São Paulo, São Paulo, Brazil, usp.br.ORCID https://orcid.org/0000-0003-0874-3995
Jéssica M Volejnik PinoEscola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, São Paulo, Brazil, unifesp.br.ORCID https://orcid.org/0000-0003-4481-3751
Philip C CalderSchool of Human Development and Health, University of Southampton, Southampton, UK, southampton.ac.uk.ORCID https://orcid.org/0000-0002-6038-710X
Steven B HeymsfieldPennington Biomedical Research Foundation, Baton Rouge, Louisiana, USA.ORCID https://orcid.org/0000-0003-1127-9425
Natasha M MachadoDepartamento de Gastroenterologia, Universidade de São Paulo, São Paulo, São Paulo, Brazil, usp.br.ORCID https://orcid.org/0000-0002-2514-9050
Dan L WaitzbergDepartamento de Gastroenterologia, Universidade de São Paulo, São Paulo, São Paulo, Brazil, usp.br.ORCID https://orcid.org/0000-0002-9196-9372

Funding

Fundação de Amparo à Pesquisa do Estado de São Paulo 2011/09612-3
6 · The paper itself

Abstract

Roux-en-Y gastric bypass (RYGB) surgery is known to improve lipid profiles in individuals with obesity, but the degree of improvement varies. Emerging evidence suggests a role for sphingolipids in modulating cholesterol metabolism. This study investigated the relationship between plasma sphingolipid changes and cholesterol improvements in women with obesity and Type 2 diabetes mellitus (T2DM) following RYGB. Patients from the SURMetaGIT study were evaluated before and 3 months after surgery. Biochemical and sphingolipid analyses, anthropometric measures, and body composition were assessed. A nonhierarchical cluster analysis assessed distinct phenotypes in response to cholesterol after surgery. The p value from multiple comparison tests was adjusted using the false discovery rate (FDR) method. A metabolite fold change [log

Indexed as

CeramidesDiabetes Mellitus, Type 2Gastric BypassLipidsObesity, MorbidAdultBiomarkersCholesterolFemaleHumansMiddle AgedPhenotypePreoperative PeriodWeight LossBiomarkersCeramidesCholesterolLipidsbariatric surgerycholesterolmetabolomicsRoux-en-Y gastric bypasssphingolipids

Identifiers

PMID42584973
PMCPMC13465188

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.