Evidence map›Paper›PMID 42584926›Full record

ArticleThe Journal of general virology2026

Herpes simplex virus type 1 interferes with signal transducer and activator of transcription 3 expression in infected mature dendritic cells.

Alexandra Birzer, Christina Drassner, Petra Muehl-Zuerbes, Christine Kuhnt, Adalbert Krawczyk, Andrea K Thoma-Kress, Alexander Steinkasserer, Linda Popella

Abstract read
In one paragraph

Article in The Journal of general virology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Alexandra BirzerHarald zur Hausen Institute of Virology, Uniklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Erlangen, Germany.
Christina DrassnerDepartment of Immune Modulation, Uniklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Erlangen, Germany.
Petra Muehl-ZuerbesDepartment of Immune Modulation, Uniklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Erlangen, Germany.
Christine KuhntDepartment of Immune Modulation, Uniklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Erlangen, Germany.
Adalbert KrawczykDepartment of Infectious Diseases, West German Centre of Infectious Diseases, University Medicine Essen, University Hospital Essen, University Duisburg-Essen, Essen, Germany.
Andrea K Thoma-KressHarald zur Hausen Institute of Virology, Uniklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Erlangen, Germany.
Alexander SteinkassererDepartment of Immune Modulation, Uniklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Erlangen, Germany.
Linda PopellaDepartment of Immune Modulation, Uniklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Erlangen, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Herpes simplex virus type 1 (HSV-1) is the prototype of the

Indexed as

Dendritic CellsHerpes SimplexHerpesvirus 1, HumanHost-Pathogen InteractionsSTAT3 Transcription FactorCells, CulturedDown-RegulationHumansImmune EvasionPhosphorylationRibonucleasesSignal TransductionViral ProteinsVirus ReplicationRibonucleasesSTAT3 protein, humanSTAT3 Transcription FactorViral Proteinsvirion host shutoff protein, Simplexvirusdendritic cellherpes simplex virus type 1 (HSV-1)IL-6 signalling pathwayimmune modulationsignal transducer and activator of transcription 3 (STAT3)

Identifiers

PMID42584926
PMCPMC13470599

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.