Evidence map›Paper›PMID 42584718›Full record

ArticleInternational ophthalmology2026

Egyptian consensus guidance for diagnosis of adults with non-infectious uveitis.

Mariam Raouf Fadel, Maha Mohamed Youssef, Noha Osama Salem, Omneya Ashraf Noureldin, Mahmoud Mohamed Soliman, Rana Hussein Amin, Lameece Moustafa Hassan, Radwa Taher Elzanaty, Shereen Hassan Aboul Naga, Mai Nasser Abd Elmohsen and 22 more

Abstract readConsensus Statement
PubMed Publisher
In one paragraph

Article in International ophthalmology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

32 authors.

Mariam Raouf FadelFaculty of Medicine, Cairo University, Giza, Egypt. Mariam_rfadel@Kasralainy.edu.eg.ORCID http://orcid.org/0000-0003-1909-3772
Maha Mohamed YoussefFaculty of Medicine, Cairo University, Giza, Egypt.ORCID http://orcid.org/0000-0003-1637-056X
Noha Osama SalemAl Mashreq Eye Center, Cairo, Egypt.ORCID http://orcid.org/0009-0000-6567-6835
Omneya Ashraf NoureldinEgyptian Railway Medical Center, Cairo, Egypt.ORCID http://orcid.org/0009-0007-3690-6110
Mahmoud Mohamed SolimanCairo University, Giza, Egypt.ORCID http://orcid.org/0000-0002-7225-3619
Rana Hussein AminCairo University, Giza, Egypt.ORCID http://orcid.org/0000-0003-3346-8067
Lameece Moustafa HassanFaculty of Medicine, Cairo University, Giza, Egypt.ORCID http://orcid.org/0000-0002-8900-7107
Radwa Taher ElzanatyFaculty of Medicine, Cairo University, Giza, Egypt.ORCID http://orcid.org/0000-0001-6163-0899
Shereen Hassan Aboul NagaFaculty of Medicine, Cairo University, Giza, Egypt.ORCID http://orcid.org/0000-0002-7167-0795
Mai Nasser Abd ElmohsenFaculty of Medicine, Cairo University, Giza, Egypt.ORCID http://orcid.org/0000-0001-9706-4446
Mohamed Refaat AbouelSaadCairo University, Giza, Egypt.ORCID http://orcid.org/0000-0001-5080-2851
Amr Mohamed Abdelaziz WassefCairo University, Giza, Egypt.ORCID http://orcid.org/0000-0001-6193-7276
Amgad El NokrashyFaculty of Medicine, Mansoura University, Mansoura, Egypt.ORCID http://orcid.org/0000-0001-6604-7133
Noha Salah MohamedFaculty of Medicine, Ain Shams University, Cairo, Egypt.ORCID http://orcid.org/0009-0001-5006-4921
Ibrahim Abuelmagd HarounNational Eye Center, Cairo, Egypt.ORCID http://orcid.org/0009-0001-3759-8734
Hind AminFaculty of Medicine, Alexandria University, Alexandria, Egypt.ORCID http://orcid.org/0009-0000-9464-0794
Asmaa Mohamad SamirFaculty of Medicine, Beni-Suef University, Beni Suef, Egypt.
Samir ShoughyDoctor Samir Eye Clinic, Alexandria, Egypt.ORCID http://orcid.org/0000-0002-9655-0669
Mohamed Abdel AzimRoyal College of Ophthalmologists, London, England.ORCID https://orcid.org/0009-0009-6306-9818
Alaa RadwanJazerat Alarab Eye and Lasik Center, Cairo, Egypt.ORCID http://orcid.org/0000-0003-4332-9634
Nehal El-GhobashyCairo University, Giza, Egypt.ORCID http://orcid.org/0000-0003-3275-7190
Mohammed Hassan Abu-ZaidFaculty of Medicine, Tanta University, Tanta, Egypt.ORCID http://orcid.org/0000-0001-8436-8598
Lobna A MagedFaculty of Medicine, Cairo University, Giza, Egypt.ORCID http://orcid.org/0000-0002-1019-2742
Ayman El GarfFaculty of Medicine, Cairo University, Giza, Egypt.ORCID http://orcid.org/0000-0001-6343-9190
Aya Tallah Haris Ibrahim EldesoukyFaculty of Medicine, Cairo University, Giza, Egypt.ORCID http://orcid.org/0000-0002-9735-6673
Sally Samy MohamedCairo University, Giza, Egypt.
Rahma A ElziatyRheumatology Division, Internal Medicine Department, Faculty of Medicine, Ain Shams University, Cairo, Egypt.ORCID http://orcid.org/0000-0002-0810-5371
Marwa A KarimDepartment of Ophthalmology, Faculty of Medicine, Ain Shams University, Cairo, Egypt.ORCID http://orcid.org/0000-0003-4523-5957
Omnia B AttiaRheumatology Division, Internal Medicine Department, Faculty of Medicine, Ain Shams University, Cairo, Egypt.
Walaa Abd El-RahmanFaculty of Medicine, Cairo University, Giza, Egypt.ORCID http://orcid.org/0000-0002-6531-2692
Doaa Ahmed TelebFaculty of Medicine, Cairo University, Giza, Egypt.ORCID http://orcid.org/0000-0001-8712-6914
Doaa Maamoun AshourFaculty of Medicine, Ain Shams University, Cairo, Egypt.ORCID http://orcid.org/0000-0003-0338-2668

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo develop the Egyptian consensus diagnostic guidance for adult non-infectious uveitis (NIU), taking into consideration the regional epidemiologic patterns and healthcare resources.

methodsA modified three-round Delphi process was conducted from January to May 2024. A multidisciplinary committee of uveitis specialists, rheumatologists, and internists formulated 24 statements across eight diagnostic domains. Experts ranked statements using a 5-point Likert scale, with consensus defined as ≥ 75% agreement, a median score ≥ 4, and an interquartile range (IQR) ≤ 1.

resultsA total of 26 experts participated in the first round, with 21 and 18 experts completing the second and third rounds, respectively (69.2% overall retention). The panel achieved consensus on all 24 diagnostic statements, emphasizing standardized examination and SUN-based inflammation grading. The panel endorsed a stepwise cost-effective systemic workup, mandating the exclusion of tuberculosis and syphilis in all adults and utilizing chest imaging (CXR/HRCT) as a baseline. MRI brain/orbit with gadolinium contrast was advised for selected cases. OCT and fluorescein angiography were recommended baseline imaging for posterior and panuveitis, while ocular sampling (aqueous or vitreous) was reserved for atypical or resistant cases. Disease description should follow SUN anatomical classification, and sight-threatening uveitis was defined by severe or prolonged inflammation that could permanently affect vision.

conclusionsThis multidisciplinary consensus provides a structured, evidence-driven framework for uveitis diagnosis tailored to the Egyptian clinical and epidemiological context. It aims to standardize local practice while aligning with international standards. Broader applicability requires local adaptation and validation.

Indexed as

Diagnostic Techniques, OphthalmologicalUveitisAdultDelphi TechniqueDiagnosis, DifferentialEgyptFluorescein AngiographyHumansDelphi consensusDiagnostic guidanceEgyptNon-infectious uveitisOcular inflammation

Identifiers

PMID42584718

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.