Evidence map›Paper›PMID 42584703›Full record

Trial reportEuropean journal of trauma and emergency surgery : official publication of the European Trauma Society2026

Non-tourniquet strategy with high-position low-perfusion in distal humeral fracture surgery: reduces swelling without increasing blood loss.

Zhimeng Wang, Xianjie Ai, Taotao Ren, Bo Wu, Kun Zhang, Zhong Li, Hanzhong Xue, Ming Li, Qian Wang

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in European journal of trauma and emergency surgery : official publication of the European Trauma Society, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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0 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Zhimeng Wang *Department of Orthopedics and Traumatology, Honghui Hospital, Xi'an Jiaotong University, No. 555, East Youyi Road, Xi'an, Shaanxi, 710000, China.
Xianjie Ai *Department of Orthopedics and Traumatology, Honghui Hospital, Xi'an Jiaotong University, No. 555, East Youyi Road, Xi'an, Shaanxi, 710000, China.
Taotao RenDepartment of Orthopedics and Traumatology, Honghui Hospital, Xi'an Jiaotong University, No. 555, East Youyi Road, Xi'an, Shaanxi, 710000, China.
Bo WuDepartment of Orthopedics and Traumatology, Honghui Hospital, Xi'an Jiaotong University, No. 555, East Youyi Road, Xi'an, Shaanxi, 710000, China.
Kun ZhangDepartment of Orthopedics and Traumatology, Honghui Hospital, Xi'an Jiaotong University, No. 555, East Youyi Road, Xi'an, Shaanxi, 710000, China.
Zhong LiDepartment of Orthopedics and Traumatology, Honghui Hospital, Xi'an Jiaotong University, No. 555, East Youyi Road, Xi'an, Shaanxi, 710000, China.
Hanzhong XueDepartment of Orthopedics and Traumatology, Honghui Hospital, Xi'an Jiaotong University, No. 555, East Youyi Road, Xi'an, Shaanxi, 710000, China.
Ming LiDepartment of Orthopedics and Traumatology, Honghui Hospital, Xi'an Jiaotong University, No. 555, East Youyi Road, Xi'an, Shaanxi, 710000, China. liming20240317@163.com.
Qian WangDepartment of Orthopedics and Traumatology, Honghui Hospital, Xi'an Jiaotong University, No. 555, East Youyi Road, Xi'an, Shaanxi, 710000, China. 17629260001@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionTo evaluate the feasibility of non-tourniquet strategy combined with "High-position Low-Perfusion" positioning in distal humeral fractures ORIF (DHF-ORIF), and to investigate its effects on perioperative blood loss, postoperative rehabilitation, and functional outcomes.

methodsProspective inclusion of patients aged 18-45 with distal humeral fractures, randomly divided into an experimental group without tourniquets (Group A) and a control group with traditional tourniquets (Group B). The Group A adopted a lateral position with high and low perfusion of the affected limb, and received intravenous injection of TXA (15 mg/kg) combined with continuous flushing with 4 ℃ physiological saline during the operation; The control group received routine use of tourniquets. PRIMARY OUTCOMES: perioperative blood loss, elbow ROM and degree of limb swelling. SECONDARY OUTCOMES: Postoperative VAS score, Mayo elbow joint score and DASH score, and incidence of complications.

resultsNo significant difference was observed in total perioperative blood loss between the Group A and the Group B (240.78 mL vs. 228.53 mL, p > 0.05). However, the Group A demonstrated significantly reduced postoperative drainage volume and hidden blood loss (p < 0.05). The Group A exhibited significantly superior outcomes in terms of VAS scores and limb swelling, compared with the control group. Additionally, elbow ROM improvement was more significant at 2-4 weeks and 2 months postoperatively in the Group A. At the 6-month follow-up, the Group A showed significantly higher Mayo scores (89.78 ± 11.89 vs. 83.55 ± 16.29) compared with the control group (p = 0.036). Furthermore, the Group A had significantly lower wound complication rates and shorter hospital stays (7.25 ± 1.53 vs. 8.11 ± 2.34 days, p = 0.037).

conclusionThe non-tourniquet strategy combined with "High-position Low-Perfusion" positioning is safe and effective for DHF-ORIF. It effectively controls postoperative swelling and pain without increasing perioperative blood loss, leading to improved clinical outcomes and quality of life.

Indexed as

Blood Loss, SurgicalEdemaFracture Fixation, InternalHumeral Fractures, DistalPatient PositioningAdolescentAdultFemaleHumansMaleMiddle AgedProspective StudiesRange of Motion, ArticularTourniquetsYoung AdultHumeral fracturesIntra-articular fracturesRehabilitationSurgeryTourniquet

Identifiers

PMID42584703
PMCPMC13469482

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.