ArticleQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2026
Differences in quality of life between early onset colorectal cancer patients compared to older patients: a qualitative study.
Article in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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1 citing paper in PubMed.
- Changes in Patient-Reported Symptoms Across Chemotherapy Cycles: A Prospective Cohort Study in an Outpatient Chemotherapy Clinic.Nursing reports (Pavia, Italy) · 2026Article
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7 authors.
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Abstract
purposeColorectal (bowel) cancer and its treatment can seriously affect a person's quality of life, including physical, social, work‑related, and emotional wellbeing. Young people with colorectal cancer experience worse psychological wellbeing, including marked emotional distress and prominent levels of anxiety. This disease is less common in people under 50, but cases of early‑onset colorectal cancer (EOCRC) are rising around the world. The object of this research was to derive a deeper understanding of the challenges and impact on quality of life faced by EOCRC compared to older patients following a colorectal cancer diagnosis.
methodRecruitment of participants from a larger mixed method project of surviving EOCRC patients from 2013 to 2023 and a matched sample of colorectal cancer patients.
resultsTwenty participants participated in interviews. Three themes (Headspace, physical impact and future) and eight corresponding sub themes encompassing poorer psychological quality of life, emotional distress and heightened anxiety faced by EOCRC. Barriers in current diagnostic services and treatment pathways more often reported by EOCRC.
conclusionOlder and younger cancer patients highlight a shift from active to passive social roles with both groups reporting substantial reductions in overall quality of life and role functioning, but longer lasting impact for EOCRC, who are focused on family, fertility, career, and survival. A review of current diagnostic services and treatment pathways is required, tailoring care for all patients and importantly address the unique needs of EOCRC.
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