Evidence map›Paper›PMID 42584365›Full record

ArticleSkin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)2026

Physiological Characteristics of Scalp Skin With High Sebum Production and the Impacts of Shampoo Cleansing.

Kuangyu Chen, Hiufung Lau, Sheldon Xu, Amy Yu, Steven Wang, Susan Biehle, Christina Gemmer, Charles Zhang, Rui Li

Abstract read
In one paragraph

Article in Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Kuangyu ChenProcter & Gamble Technology (Beijing) Co. Ltd., Beijing, China.
Hiufung LauProcter & Gamble International Operations SA Singapore Branch, Singapore, Singapore.
Sheldon XuProcter & Gamble Technology (Beijing) Co. Ltd., Beijing, China.
Amy YuProcter & Gamble Technology (Beijing) Co. Ltd., Beijing, China.
Steven WangProcter & Gamble Technology (Beijing) Co. Ltd., Beijing, China.
Susan BiehleThe Procter & Gamble Company Mason Business Center, Mason, USA.
Christina GemmerThe Procter & Gamble Company Mason Business Center, Mason, USA.
Charles ZhangProcter & Gamble Technology (Beijing) Co. Ltd., Beijing, China.
Rui LiProcter & Gamble International Operations SA Singapore Branch, Singapore, Singapore.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe scalp has a higher sebum content than other body areas, leading to issues such as itchiness, dandruff and discomfort. In individuals with scalp seborrhoea, the relationships between sebum levels, hydration, barrier function and self-perceived scalp condition remain poorly understood.

aimsThis study aimed to explore scalp sebum accumulation and associated physiological properties, as well as to evaluate the impact of a single shampoo cleansing efficacy on sebum levels.

methodsThis study involved an Asian population with self-reported scalp oiliness and dandruff. Participants with elevated scalp sebum levels (>75 µg/cm

resultsAt baseline, the scalp exhibited higher sebum levels, lower hydration and weaker barrier function compared to the frontal hairline and nape. Scalp hydration negatively correlated with sebum levels measured in scalp pores. Hydroxyoctadecadienoic acid (HODE), an oxidative stress biomarker, positively correlated with scalp sebum. Interestingly, HODE levels also showed a positive correlation with participants' self-reported dandruff and itchiness. After single wash with a shampoo containing 0.5% piroctone olamine (PO), surface and pore sebum levels were significantly reduced, as well as HODE levels.

conclusionThis study underscores the significance of sebum levels and composition in scalp health among Chinese individuals, emphasizing the need for shampoos that remove excess sebum while preserving the scalp barrier.

Indexed as

Hair PreparationsScalpSebumAdultDandruffDermatitis, SeborrheicFemaleHumansMaleMiddle AgedOxidative StressScalp DermatosesYoung AdultHair Preparationsbarrier functiondandruffHODE (Hydroxyoctadecadienoic acid)hydrationitchinessoxidative stress

Identifiers

PMID42584365
PMCPMC13464430

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.