Evidence map›Paper›PMID 42584358›Full record

ArticleNanomaterials (Basel, Switzerland)2026

Transplacental Toxicity of Zinc Oxide Nanoparticles: Maternal-Fetal DNA Damage and Organ Accumulation.

Elsayed I Salim, Naira M Al-Fiky, Khaled Y Abdel-Halim, Dina M M AlSadek, Haitham A Badr, Mohamed Monir Hammad, Hassan A Basha, Fouad A Abou-Zaid, Hafiz Ahmed

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nanomaterials (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Elsayed I SalimResearch Laboratory of Molecular Carcinogenesis, Department of Zoology, Faculty of Science, Tanta University, Tanta 31527, Egypt.
Naira M Al-FikyResearch Laboratory of Molecular Carcinogenesis, Department of Zoology, Faculty of Science, Tanta University, Tanta 31527, Egypt.
Khaled Y Abdel-HalimDepartment of Mammalian & Aquatic Toxicology, Central Agricultural Pesticides Laboratory (CAPL), Agricultural Research Center (ARC), Dokki, Giza 12618, Egypt.ORCID 0000-0003-3389-2693
Dina M M AlSadekDepartment of Histology and Cytology, Faculty of Veterinary Medicine, Zagazig University, Zagazig 44511, Egypt.ORCID 0000-0001-5843-1119
Haitham A BadrDepartment of Biochemistry, Faculty of Agriculture, Zagazig University, Zagazig 44511, Egypt.ORCID 0000-0002-2403-3785
Mohamed Monir HammadDepartment of Zoology, Faculty of Science, Alexandria University, Alexandria 21568, Egypt.
Hassan A BashaResearch Laboratory of Molecular Carcinogenesis, Department of Zoology, Faculty of Science, Tanta University, Tanta 31527, Egypt.
Fouad A Abou-ZaidResearch Laboratory of Molecular Carcinogenesis, Department of Zoology, Faculty of Science, Tanta University, Tanta 31527, Egypt.
Hafiz AhmedGlycoMantra Inc., 1450 South Rolling Road, Baltimore, MD 21227, USA.

Funding

Targeting galectin-3 to overcome insulin resistance in type 2 diabetesR44DK125126 · NIDDK · GLYCOMANTRA, INC. · PI AHMED, HAFIZ · 2023 to 2024
$3.7M
Targeting galectin-3 to overcome insulin resistance in type 2 diabetesR43DK125126 · NIDDK · GLYCOMANTRA, INC. · PI AHMED, HAFIZ · 2020 to 2020
$300k
NIDDK NIH HHS R43 DK125126NIDDK NIH HHS R44 DK125126NIH HHS 5R44DK125126-03
6 · The paper itself

Abstract

Nanomaterials (NMs) offer substantial technological advantages, yet their potential adverse biological effects remain a critical concern. This study investigates the maternal-fetal toxicity of zinc oxide nanoparticles (ZnONPs) following a single intravenous (i.v.) administration in vivo, focusing on oxidative DNA damage, cytotoxicity, and transplacental transfer. The median lethal dose (LD

Indexed as

8-hydroxydeoxyguanosine (8-OHdG)maternal–fetal toxicitynanotoxicologyorgan accumulationoxidative DNA damagetransplacental transferzinc oxide nanoparticles

Identifiers

PMID42584358
PMCPMC13468023

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.