Evidence map›Paper›PMID 42584164›Full record

ArticlemSphere2026

Expanded prevalence of group 4 capsule expression and its genetic requirements in a broad array of

Brock W Brethour, Tao Wu, Bing Guo, Megan D Broussard, David A Rasko, Eileen M Barry

Abstract read
In one paragraph

Article in mSphere, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Brock W BrethourCenter for Vaccine Development and Global Health, University of Maryland School of Medicine, Baltimore, Maryland, USA.ORCID 0009-0002-1279-5763
Tao WuCenter for Vaccine Development and Global Health, University of Maryland School of Medicine, Baltimore, Maryland, USA.
Bing GuoCenter for Vaccine Development and Global Health, University of Maryland School of Medicine, Baltimore, Maryland, USA.ORCID 0000-0002-3998-5981
Megan D BroussardCenter for Vaccine Development and Global Health, University of Maryland School of Medicine, Baltimore, Maryland, USA.ORCID 0009-0008-5042-772X
David A RaskoDepartment of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, Maryland, USA.ORCID 0000-0002-7337-7154
Eileen M BarryCenter for Vaccine Development and Global Health, University of Maryland School of Medicine, Baltimore, Maryland, USA.ORCID 0000-0002-5326-0047

Funding

Project 3 - Human colonoids as a model for the pathobiology of EHECP01AI125181 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI KAPER, JAMES B · 2016 to 2025
$18.6M
Probiotic yeast secreting single-domain antibodies to prevent Clostridium difficile and Campylobacter jejuni diseaseU19AI142725 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI SZTEIN, MARCELO B. · 2019 to 2023
$12.5M
Systems-Level Research in Microbial PathogenesisT32AI162579 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI NICHOLAS H CARBONETTI, Julie Dunning Hotopp · 2022 to 2026
$1.7M
National Institute of Allergy and Infectious Diseases T32AI162579National Institute of Allergy and Infectious Diseases U19AI142725, P01AI125181NIAID NIH HHS P01 AI125181NIAID NIH HHS T32 AI162579NIAID NIH HHS U19 AI142725
6 · The paper itself

Abstract

The expression of a group 4 capsule (G4C) has been identified in IMPORTANCE:

Indexed as

Bacterial CapsulesShigellaDysentery, BacillaryGene Expression Regulation, BacterialGenome, BacterialHumansOperonSerogroupShigella flexneriShigella sonneicapsulegroup 4 capsulehost–pathogen interactionsO-antigenShigella

Identifiers

PMID42584164
PMCPMC13621845

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.