Evidence map›Paper›PMID 42584082›Full record

ArticleChemSusChem2026

Boosting Singlet Oxygen Generation in Donor-Acceptor Binary Hydrogen-Bonded Organic Frameworks for Photodynamic Antibacterium.

Jiaqi Han, Hang Tian, Peiyan Li, Chenghao Zhang, Peng Li

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ChemSusChem, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jiaqi HanState Key Laboratory of Porous Materials for Separation and Conversion, Shanghai Key Laboratory of Molecular Catalysis and Innovative Materials, College of Smart Materials and Future Energy, Fudan University, Shanghai, P. R. China.
Hang TianGuangxi Key Laboratory of Petrochemical Resource Processing and Process Intensification Technology, School of Chemistry and Chemical Engineering, Guangxi University, Nanning, P. R. China.
Peiyan LiGuangxi Key Laboratory of Clean Pulp & Papermaking and Pollution Control, School of Light Industry and Food Engineering, Guangxi University, Nanning, P. R. China.
Chenghao ZhangGuangxi Key Laboratory of Clean Pulp & Papermaking and Pollution Control, School of Light Industry and Food Engineering, Guangxi University, Nanning, P. R. China.
Peng LiState Key Laboratory of Porous Materials for Separation and Conversion, Shanghai Key Laboratory of Molecular Catalysis and Innovative Materials, College of Smart Materials and Future Energy, Fudan University, Shanghai, P. R. China.ORCID https://orcid.org/0000-0002-4273-4577

Funding

National Natural Science Foundation of China 22575053Science and Technology Commission of Shanghai Municipality 2024ZDSYS02
6 · The paper itself

Abstract

Incorporating donor-acceptor (D-A) architectures into hydrogen-bonded organic frameworks (HOFs) offers a promising route to boost exciton utilization for photodynamic therapy (PDT). However, conventional strategies that fuse donor and acceptor moieties into a single building block pose severe synthetic challenges. Herein, we address this limitation via a modular binary assembly approach, constructing D-A HOFs in which spatially separated donor and acceptor units are precisely integrated through hydrogen-bonding networks instead of covalent conjugation. This modular design greatly simplifies synthesis by allowing independent optimization of D and A components, reduces the bandgap to 1.98 eV (from 2.63 eV for the single building block), and enhances singlet oxygen generation by 4-8 times, leading to markedly improved PDT antibacterial efficacy. This work not only provides fundamental insights into exciton manipulation in hydrogen-bonded systems but also establishes a generalizable paradigm for developing high-performance PDT materials through supramolecular D-A engineering.

Indexed as

antibacterial applicationsdonor–acceptor (D–A) architecturehydrogen‐bonded organic frameworks (HOFs)photodynamic therapysinglet oxygen generation

Identifiers

PMID42584082
PMCPMC13464059

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.