Evidence map›Paper›PMID 42583909›Full record

ArticleBioMed research international2026

Comparative Analysis of Antimicrobial Resistance Profiles in Enterobacteriaceae Isolates From Outpatient Carriages and Clinical Infections in an Urban Setting.

Kobina Amandzé Adams Kofi, Stéphane Kouadio Koffi, Mathieu Kra Adou Koffi, Alexia Yapi Ivan, N Guessan Carole Obouayeba Djaman, Aboubacar Bamba, Flora Ahonzo, Kacou N Douba Adèle

Abstract readComparative Study
In one paragraph

Article in BioMed research international, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Kobina Amandzé Adams KofiBiology and Health Laboratory, Biosciences Training and Research Unit, Université Félix Houphouët-Boigny, Abidjan, Côte d'Ivoire, univ-fhb.edu.ci.ORCID https://orcid.org/0009-0007-0783-9422
Stéphane Kouadio KoffiBacteriology-Virology Unit, University Hospital of Treichville, Abidjan, Côte d'Ivoire.ORCID https://orcid.org/0000-0002-7141-0774
Mathieu Kra Adou KoffiBiology and Health Laboratory, Biosciences Training and Research Unit, Université Félix Houphouët-Boigny, Abidjan, Côte d'Ivoire, univ-fhb.edu.ci.
Alexia Yapi IvanMedical Sciences Training and Research Unit, Université Félix Houphouët-Boigny, Abidjan, Côte d'Ivoire, univ-fhb.edu.ci.
N Guessan Carole Obouayeba DjamanBiology and Health Laboratory, Biosciences Training and Research Unit, Université Félix Houphouët-Boigny, Abidjan, Côte d'Ivoire, univ-fhb.edu.ci.
Aboubacar BambaBiology and Health Laboratory, Biosciences Training and Research Unit, Université Félix Houphouët-Boigny, Abidjan, Côte d'Ivoire, univ-fhb.edu.ci.ORCID https://orcid.org/0009-0002-2792-7140
Flora AhonzoBacteriology-Virology Unit, University Hospital of Treichville, Abidjan, Côte d'Ivoire.ORCID https://orcid.org/0009-0009-2660-1297
Kacou N Douba AdèleMedical Sciences Training and Research Unit, Université Félix Houphouët-Boigny, Abidjan, Côte d'Ivoire, univ-fhb.edu.ci.ORCID https://orcid.org/0000-0002-5357-7490

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe emergence and spread of multidrug-resistant Enterobacteriaceae (MDR-E) in community and hospital settings constitute a major public health challenge, particularly in densely populated urban areas. Although antimicrobial resistance among clinical isolates has been repeatedly studied, resistance profiles of intestinal carriage strains remain scarcely reported, despite their potential role as important reservoirs of resistance genes. An integrated approach including both carriage and clinical isolates is therefore necessary to better understand antimicrobial resistance dynamics.

objectiveThis study is aimed at comparing the antibiotic resistance profiles of Enterobacteriaceae isolated from intestinal carriage in outpatients and those from clinical infections.

methodsA total of 196 strains, including Escherichia coli, Klebsiella pneumoniae, and Enterobacter cloacae, were analyzed, comprising 60 carriage isolates and 136 clinical isolates. Antimicrobial susceptibility testing was performed using the disk diffusion method according to CA-SFM guidelines. Resistance profiles were classified as multidrug-resistant (MDR), extensively drug-resistant (XDR), or pandrug-resistant (PDR) based on the criteria of Magiorakos et al., and the multiple antibiotic resistance (MAR) index was calculated.

resultsOverall, a high prevalence of MDR strains was observed (86.73%) in both groups, with distinct resistance patterns depending on the source. Carriage strains showed higher resistance to cephalosporins, fluoroquinolones, monobactams, tetracyclines, and sulfonamides (MAR index: 0.76 ± 0.09), whereas clinical strains exhibited increased resistance to aminoglycosides and carbapenems (MAR index: 0.65 ± 0.18). XDR (6.12%) and PDR (1.02%) phenotypes were mainly identified among clinical isolates.

conclusionThese findings emphasize the role of intestinal carriage as a reservoir of antimicrobial resistance and support the need for integrated community-hospital surveillance strategies in urban settings.

Indexed as

Drug Resistance, Multiple, BacterialEnterobacteriaceaeEnterobacteriaceae InfectionsAdultAnti-Bacterial AgentsFemaleHumansMaleMicrobial Sensitivity TestsMiddle AgedOutpatientsUrban PopulationAnti-Bacterial Agentsantimicrobial resistance dynamicsclinical infectionscommunity–hospital surveillanceintestinal carriage strainsmultidrug-resistant Enterobacteriaceae

Identifiers

PMID42583909
PMCPMC13463431

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.